Chronic kidney disease (CKD) is a debilitating pathology with various causal factors,
culminating in end stage renal disease (ESRD) requiring dialysis or kidney transplantation …

The most problematic issue in clinical nephrology is the relentless and progressive increase
in patients with ESRD (end-stage renal disease) worldwide. The impact of diabetic …

Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the
globe and is one of the main complications in patients with type 1 and 2 diabetes. The …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are worldwide public health
problems affecting millions of people and have rapidly increased in prevalence in recent …

Chronic kidney disease is highly prevalent worldwide. The decline of renal function is
associated with inadequate removal of a variety of uremic toxins that exert detrimental …

BACKGROUND Diabetic nephropathy is a major risk of end-stage kidney disease. Many
complex factors relate to the progression of diabetic nephropathy. Using nonobese type 2 …

With the global increase of the elderly population, the improvement of the treatment for
various aging-related diseases and the extension of a healthy lifespan have become some …

Local inflammation is thought to contribute to the progression of diabetic nephropathy. The
vitamin D receptor (VDR) activator paricalcitol has an antiproteinuric effect in human diabetic …

Vitamin D has been implicated in the pathophysiology of extraskeletal conditions such as
hypertension, kidney disease, and diabetes via its ability to negatively regulate the renin …

The anti-inflammatory, antifibrotic, and antiproteinuric properties of vitamin D have been
defined in studies using active vitamin D analogs. In this prospective observational study we …