Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease,
is the leading cause of visual impairment in diabetic patients. Many clinical features …

The retina, owing to its cellular anatomy and physical location, is susceptible to generating
reactive oxygen species (ROS), which are associated with several major retinal diseases …

Diabetic retinopathy is a neurovascular complication of diabetes and the main cause of
vision loss in adults. Glial cells have a key role in maintenance of central nervous system …

Oxidative stress is one of the major causes of most age-dependent neurodegenerative
disorders. Neurons accumulate oxidative damage over time due to post-mitotic cells. Thus …

Purpose. Diabetic retinopathy (DR) is an ocular disease caused by diabetes and may lead
to vision impairment and even blindness. Oxidative stress and inflammation are two key …

The science of diabetes care has progressed to provide a better understanding of the
oxidative and inflammatory lesions and pathophysiology of the neuro-vascular unit within …

Background Diabetic retinopathy (DR) is a common cause of visual impairment. Apigenin
has been shown to have antiangiogenic effects in various diseases. Our study aimed to …

Objectives The aim of this study was to investigate how melatonin administration affects
retinal oxidative damage and retinal SIRT1 gene activation in diabetic elderly female rat …

Recent advances in the research of the mammalian target of the rapamycin (mTOR)
signalling pathway demonstrated that mTOR is a robust therapeutic target for ocular …

Diabetes mellitus (DM) is now recognized as a system-wide, autoimmune, inflammatory,
microvascular disorder, which, in the retina and brain results in severe multifocal injury now …