The human virome and its crosslink with glomerulonephritis and IgA nephropathy

F Sallustio, A Picerno, F Montenegro… - International Journal of …, 2023 - mdpi.com
The prokaryotic, viral, fungal, and parasitic microbiome exists in a highly intricate connection
with the human host. In addition to eukaryotic viruses, due to the existence of various host …

Metagenomic analysis of double-stranded DNA viruses in healthy adults

KM Wylie, KA Mihindukulasuriya, Y Zhou, E Sodergren… - BMC biology, 2014 - Springer
Abstract Background The Human Microbiome Project (HMP) was undertaken with the goal
of defining microbial communities in and on the bodies of healthy individuals using high …

Hubs and Bottlenecks in Protein-Protein Interaction Networks

C Nithya, M Kiran, HA Nagarajaram - Reverse engineering of regulatory …, 2023 - Springer
Protein-protein interaction networks (PPINs) represent the physical interactions among
proteins in a cell. These interactions are critical in all cellular processes, including signal …

VISDB: a manually curated database of viral integration sites in the human genome

D Tang, B Li, T Xu, R Hu, D Tan, X Song… - Nucleic acids …, 2020 - academic.oup.com
Virus integration into the human genome occurs frequently and represents a key driving
event in human disease. Many studies have reported viral integration sites (VISs) proximal …

Benchmarking enrichment analysis methods with the disease pathway network

D Buzzao, M Castresana-Aguirre… - Briefings in …, 2024 - academic.oup.com
Enrichment analysis (EA) is a common approach to gain functional insights from genome-
scale experiments. As a consequence, a large number of EA methods have been …

Systems bioinformatics reveals possible relationship between COVID-19 and the development of neurological diseases and neuropsychiatric disorders

A Onisiforou, GM Spyrou - Viruses, 2022 - mdpi.com
Coronavirus Disease 2019 (COVID-19) is associated with increased incidence of
neurological diseases and neuropsychiatric disorders after infection, but how it contributes …

Progress in computational studies of host–pathogen interactions

H Zhou, J Jin, L Wong - Journal of bioinformatics and computational …, 2013 - World Scientific
Host–pathogen interactions are important for understanding infection mechanism and
developing better treatment and prevention of infectious diseases. Many computational …

Prediction and Comparison of SalmonellaHuman and SalmonellaArabidopsis Interactomes

S Schleker, J Garcia‐Garcia… - Chemistry & …, 2012 - Wiley Online Library
Salmonellosis caused by Salmonella bacteria is a food‐borne disease and a worldwide
health threat causing millions of infections and thousands of deaths every year. This …

[HTML][HTML] A scheme for inferring viral-host associations based on codon usage patterns identifies the most affected signaling pathways during COVID-19

JK Das, S Chakraborty, S Roy - Journal of Biomedical Informatics, 2021 - Elsevier
Understanding the molecular mechanism of COVID-19 pathogenesis helps in the rapid
therapeutic target identification. Usually, viral protein targets host proteins in an organized …

Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches

A Onisiforou, GM Spyrou - Briefings in Bioinformatics, 2021 - academic.oup.com
During the course of a viral infection, virus–host protein–protein interactions (PPIs) play a
critical role in allowing viruses to replicate and survive within the host. These interspecies …