[HTML][HTML] Rhenium (I) derivatives of aminoquinoline and imidazolopiperidine-based ligands: synthesis, in vitro and in silico biological evaluation against Plasmodium …
SN Sovari, TM Golding, M Mbaba, R Mohunlal… - Journal of Inorganic …, 2022 - Elsevier
A small library of aminoquinoline and imidazolopiperidine (IMP)-based ligands, containing
the 1, 2, 3-triazole moiety, and their corresponding tricarbonyl rhenium complexes were …
the 1, 2, 3-triazole moiety, and their corresponding tricarbonyl rhenium complexes were …
Copper borate (CuB 4 O 7)-promoted multi-component green synthesis of 2, 4, 5-triarylimidazole derivatives and evidence of in situ conversion of copper borate (CuB …
A green, efficient, and straightforward methodology for the three-component synthesis of 2,
4, 5-triarylimidazole has been developed under solvent-free conditions using …
4, 5-triarylimidazole has been developed under solvent-free conditions using …
Diversification of quinoline-triazole scaffolds with CORMs: Synthesis, in vitro and in silico biological evaluation against Plasmodium falciparum
A discrete series of tricarbonyl manganese and rhenium complexes conjugated to a
quinoline-triazole hybrid scaffold were synthesised and their inhibitory activities evaluated …
quinoline-triazole hybrid scaffold were synthesised and their inhibitory activities evaluated …
Design, synthesis and biological evaluation of mono-and bisquinoline methanamine derivatives as potential antiplasmodial agents
Several classes of antimalarial drugs are currently available, although issues of toxicity and
the emergence of drug resistant malaria parasites have reduced their overall therapeutic …
the emergence of drug resistant malaria parasites have reduced their overall therapeutic …
Adsorption to the Surface of Hemozoin Crystals: Structure‐Based Design and Synthesis of Amino‐Phenoxazine β‐Hematin Inhibitors
T Olivier, L Loots, M Kok, M De Villiers… - …, 2022 - Wiley Online Library
In silico adsorption of eight antimalarials that inhibit β‐hematin (synthetic hemozoin)
formation identified a primary binding site on the (001) face, which accommodates inhibitors …
formation identified a primary binding site on the (001) face, which accommodates inhibitors …
[PDF][PDF] Synthesis, Characterisation and Binding Evaluation of New 6-Amidinoindole Compound as the Potential Heme Binder
In this study, the new compound 6-amidinoindole 3 were synthesized by hydrogenating the
amidoxime unit in a high yield. The compound was characterized by FTIR, 1H NMR, 13C …
amidoxime unit in a high yield. The compound was characterized by FTIR, 1H NMR, 13C …
Hemisynthesis of Pentacyclic Triterpenoids from Diospyros foxworthyi with In vitro and In silico Anti-malarial Evaluation
MS Abd Ghani, NAL Abu Bakar… - Current Organic …, 2024 - ingentaconnect.com
A total of twelve pentacyclic triterpenoid derivatives based on betulin (1) and lupeol (2)
scaffolds isolated from Diospyros foxworthyi were hemisynthesized by acylation or …
scaffolds isolated from Diospyros foxworthyi were hemisynthesized by acylation or …
Recent Highlights in Anti‐Infective Medicinal Chemistry from South Africa
Global advancements in biological technologies have vastly increased the variety of and
accessibility to bioassay platforms, while simultaneously improving our understanding of …
accessibility to bioassay platforms, while simultaneously improving our understanding of …