Viral hijacking of cellular metabolism

SK Thaker, J Ch'ng, HR Christofk - BMC biology, 2019 - Springer
This review discusses the current state of the viral metabolism field and gaps in knowledge
that will be important for future studies to investigate. We discuss metabolic rewiring caused …

Obesity and the risk and outcome of infection

R Huttunen, J Syrjänen - International journal of obesity, 2013 - nature.com
The interactions between obesity and infectious diseases have recently received increasing
recognition as emerging data have indicated an association between obesity and poor …

Extrahepatic manifestations of chronic hepatitis C virus infection

P Cacoub, C Comarmond, F Domont… - Therapeutic …, 2016 - journals.sagepub.com
During hepatitis C virus (HCV) chronic infection, extrahepatic manifestations are frequent
and polymorphous. This article reports on a large cohort of patients with HCV-related …

The etiology of hepatocellular carcinoma and consequences for treatment

AJ Sanyal, SK Yoon, R Lencioni - The oncologist, 2010 - academic.oup.com
Most patients with hepatocellular carcinoma (HCC) have liver cirrhosis, which develops
following long periods of chronic liver disease. Cirrhosis is characterized by a decrease in …

[PDF][PDF] Global challenges in liver disease

R Williams - Hepatology, 2006 - Wiley Online Library
Immigration, cheap air travel, and globalization are all factors contributing to a worldwide
spread of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. End‐stage chronic …

Immunobiology and pathogenesis of viral hepatitis

LG Guidotti, FV Chisari - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Among the many viruses that are known to infect the human liver, hepatitis B virus (HBV)
and hepatitis C virus (HCV) are unique because of their prodigious capacity to cause …

[HTML][HTML] Extrahepatic manifestations of chronic hepatitis C virus infection

P Cacoub, L Gragnani, C Comarmond… - Digestive and Liver …, 2014 - Elsevier
Hepatitis C virus (HCV) infected patients are known to be at risk of developing liver
complications ie cirrhosis and liver cancer. However, the risks of morbidity and mortality are …

Repositioning metformin for cancer prevention and treatment

BJ Quinn, H Kitagawa, RM Memmott, JJ Gills… - Trends in Endocrinology …, 2013 - cell.com
Metformin is the most commonly prescribed drug for type 2 diabetes (T2DM). Retrospective
studies show that metformin is associated with decreased cancer risk. This historical …

Natural history of acute and chronic hepatitis C

B Maasoumy, H Wedemeyer - Best practice & research Clinical …, 2012 - Elsevier
Hepatitis C virus (HCV) infection remains a major global health burden. Hepatitis C causes
significant liver-related morbidity and mortality due to hepatic decompensation and …

[HTML][HTML] Epidemiology and natural history of hepatitis C virus infection

MH Lee, HI Yang, Y Yuan, G L'Italien… - World journal of …, 2014 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) affects 130-210 million people worldwide and is one of the major
risk factors for hepatocellular carcinoma. Globally, at least one third of hepatocellular …