Elucidating of Fluconazole Cocrystallization With a Cutting-Edge Nutraceutical Coformer for Enhanced Formulation Strategies
P Vithlapara, M Chotaliya, D Mori, K Dudhat - Journal of Pharmaceutical …, 2024 - Springer
Introduction This current research reports the synthesis and characterization of a cocrystal of
Fluconazole (FLU), a widely used antifungal drug, with a nutraceutical coformer (NCF) that …
Fluconazole (FLU), a widely used antifungal drug, with a nutraceutical coformer (NCF) that …
Revealing Solid–Liquid Equilibrium Behavior of 4-Fluorobenzoic Acid in 12 Pure Solvents from 283.15 to 323.15 K by Experiments and Molecular Simulations
The solubility of 4-fluorobenzoic acid (4FBA) in 12 pure solvents (methanol, ethanol, 1-
propanol, 2-propanol, 1-butanol, isobutanol, 1-pentanol, ethyl formate, methyl acetate, ethyl …
propanol, 2-propanol, 1-butanol, isobutanol, 1-pentanol, ethyl formate, methyl acetate, ethyl …
Synthon Approach in Crystal Engineering to Modulate Physicochemical Properties in Organic Salts of Chlorpropamide
AM Menon, NN Sidhartha, I Shruti… - Molecular …, 2024 - ACS Publications
The formulation of drug with improved bioavailability is always challenging and
indispensable in the field of pharmaceutics. The control of intermolecular interactions via …
indispensable in the field of pharmaceutics. The control of intermolecular interactions via …
Importance of Structural Databases, Molecular Pharmacophores, Supramolecular Heterosynthons, and Artificial Intelligence–Machine Learning–Neural Network Tools …
AK Nangia - Crystal Growth & Design, 2024 - ACS Publications
The progress and growth of drug discovery and development (DDD) in the past five decades
are reviewed in terms of the changing trends over the years. The importance of the …
are reviewed in terms of the changing trends over the years. The importance of the …
Green Mechanochemical Preparation of Cocrystal Polymorphs: Significant Effect of Intermediates and Solvents
L Qi, C Li, X Cheng, H Hao, C Xie - Crystal Growth & Design, 2024 - ACS Publications
Recently, green mechanochemical methods have received increasing attention. The fact
that intermediates may exist during the milling process has also been gradually revealed …
that intermediates may exist during the milling process has also been gradually revealed …
Enhanced Dissolution and Diffusion of Ribociclib by Salt Formation with Fluorobenzoic Acid Coformers
S Sangwan, B Swapna, AK Nangia - Crystal Growth & Design, 2024 - ACS Publications
Ribociclib (RBC) is an anticancer drug of poor aqueous solubility and low permeability. In
this study, we report the improvement in the physicochemical properties of RBC, such as …
this study, we report the improvement in the physicochemical properties of RBC, such as …
Multi-component forms of the 2nd generation H1 receptor antagonist drug, Bilastine and its enhanced physicochemical characteristics
Bilastine (BIL) is a novel 2nd generation antihistamine medication is used to treat symptoms
of chronic urticaria and allergic rhinitis. However, its poor solubility limits its therapeutic …
of chronic urticaria and allergic rhinitis. However, its poor solubility limits its therapeutic …
Enhancing the Stability, Solubility, and Antioxidant Activity of Cinchonine through Pharmaceutical Cocrystallization
Y Zhou, Y Tu, J Yang, K Qian, X Liu, Q Fu, X Xu… - Pharmaceutical …, 2024 - Springer
Purpose Cinchoninze hydrochloride solves the problem of the low solubility of cinchonine,
but it is unstable and susceptible to deliquescence. In this study, we designed and prepared …
but it is unstable and susceptible to deliquescence. In this study, we designed and prepared …