Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …

Intrinsically disordered proteins (IDPs) and intrinsically disordered protein regions (IDPRs)
are functional proteins and domains that devoid stable secondary and/or tertiary structure …

(MS) and MS-driven proteomics have continued to develop as the premier tools for
characterizing proteome composition, structure, and function. 2 The new era of proteomics …

Mass spectrometry is well-established as one of the primary methods used to characterize
peptides and proteins. New advances in instrumentation and innovative analytical workflows …

The depth of proteomic analyses is often limited by the overwhelming proportion of
confounding background ions that compromise the identification and quantification of low …

Histone post-translational modifications (PTMs) are one of the main mechanisms of
epigenetic regulation. Dysregulation of histone PTMs leads to many human diseases, such …

Introduction: Acetylation is a widely occurring post-translational modification (PTM) of
proteins that plays a crucial role in many cellular physiological and pathological processes …

Despite often minute concentrations in vivo, d-amino acid containing peptides (DAACPs) are
crucial to many life processes. Standard proteomics protocols fail to detect them as d/l …

The field of proteomics is increasingly concerned with the diversity and functional relevance
of protein modifications. Differential ion mobility spectrometry (DMS) is emerging as a tool to …

Since its inception in the early 20th century, mass spectrometry (MS) has become a
significant method to analyze molecules. In the century since JJ Thomson's first use of MS in …