3-(Bromoacetyl) coumarins: unraveling their synthesis, chemistry, and applications

MM Abdou, A Abu-Rayyan, AG Bedir, S Abdel-Fattah… - RSC …, 2021 - pubs.rsc.org
This review emphasizes recent developments in synthetic routes of 3-(bromoacetyl)
coumarin derivatives. Also, chemical reactions of 3-(bromoacetyl) coumarins as versatile …

Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant antimicrobial …

S Kumar, V Saini, IK Maurya, J Sindhu, M Kumari… - PloS one, 2018 - journals.plos.org
The control of antimicrobial resistance (AMR) seems to have come to a dead end. The major
consequences of the use and abuse of antibacterial drugs are the development of resistant …

3‐Bromoacetylcoumarin, a Crucial Key for Facial Synthesis of Biological Active Compounds

N Hosseini Nasab, F Azimian, HG Kruger… - …, 2022 - Wiley Online Library
Compounds containing the coumarin scaffold are widely used in the pharmaceutical and
medicinal industries. The biological activities of coumarin containing derivatives make the …

Experimental and Computational Validation of Structural Features and BSA Binding Tendency of 5‐Hydroxy‐5‐trifluoromethyl‐3‐arylpyrazolines

R Kataria, D Vashisht, P Rani, J Sindhu… - …, 2021 - Wiley Online Library
Bovine serum albumin (BSA) serves as a model protein to explore drug‐protein interactions
due to its structural similarities with Human serum albumin (HSA). In this report, the binding …

Insight into the therapeutic potential of pyrazole‐thiazole hybrids: A comprehensive review

G Sumran, M Sharma, R Aggarwal - Archiv der Pharmazie, 2024 - Wiley Online Library
Several pyrazole‐thiazole hybrids featuring two potentially bioactive pharmacophores with
or without linker have been synthesized using the molecular hybridization approach as …

Synthesis of new pharmacologically oriented heterocyclic ensembles,[2-(1H-pyrazol-1-yl) thiazol-4-yl] furoxans

MA Epishina, AS Kulikov, LL Fershtat… - Mendeleev …, 2019 - elibrary.ru
The effective synthesis of pharmacologically oriented heterocyclic ensembles,[2-(1H-pyrazol-
1-yl) thiazol-4-yl] furoxans, comprising furoxan moiety as NO-donor and pharmacophoric …

Recent advances in the synthesis and biological activities of 3-aminoalkyl/3-amidoalkyl-4-hydroxycoumarin derivatives

A Olyaei, M Sadeghpour - Synthetic Communications, 2023 - Taylor & Francis
Coumarins and its derivatives are an important class of heterocyclic compounds that have
attracted much attention because of their diverse therapeutic, biological, and …

Trifluoromethyl‐β‐dicarbonyls as Versatile Synthons in Synthesis of Heterocycles

G Sumran, N Jain, P Kumar… - Chemistry–A European …, 2024 - Wiley Online Library
Trifluoromethyl group relishes a privileged position in the realm of medicinal chemistry
because its incorporation into organic molecules often enhances the bioactivity by altering …

[PDF][PDF] Synthetic approaches toward certain structurally related antimicrobial thiazole derivatives (2010-2020)

A Hassan, HA Hassan, D Abdelhamid… - …, 2021 - triggered.edina.clockss.org
In the present literature review, we comprehensively discuss different methods of synthesis
of published antimicrobial thiazole derivatives in the last decade mainly those which showed …

A review on synthesis of coumarin derived Schiff's base metal complexes and their control over E. coli bacterium

A Sharma, S Devi, S Kumar - Main Group Chemistry, 2024 - journals.sagepub.com
Nowadays, the dilemma of drug resistance to antibacterial strains is of huge concern.
Among the bacteria, Escherchia coli (E. coli) is the major pathogen, which is found in human …