[HTML][HTML] Efficacy and safety of recently approved drugs for sickle cell disease: a review of clinical trials

MA Ali, A Ahmad, H Chaudry, W Aiman, S Aamir… - Experimental …, 2020 - Elsevier
Highlights•VOC episodes and low hemoglobin levels are major complications of SCD.•L-
Glutamine decreases the episodes of VOC.•Voxelotor increases hemoglobin levels and …

A critical evaluation of crizanlizumab for the treatment of sickle cell disease

NR Karki, K Saunders, A Kutlar - Expert Review of Hematology, 2022 - Taylor & Francis
Introduction P-selectin is a key adhesion molecule in the pathogenesis of sickle cell disease,
including acute painful event (s). Many of the mediators activated in prototypical pain crisis …