Mechanisms and consequences of oxidative stress in lung disease: therapeutic implications for an aging populace

L Hecker - American Journal of Physiology-Lung Cellular …, 2018 - journals.physiology.org
The rapid expansion of the elderly population has led to the recent epidemic of age-related
diseases, including increased incidence and mortality of chronic and acute lung diseases …

The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti‐inflammatory response, and regulatory T cells

DH Lewis, DL Chan, D Pinheiro… - Journal of Veterinary …, 2012 - Wiley Online Library
Sepsis, the systemic inflammatory response to infection, represents the major cause of death
in critically ill veterinary patients. Whereas important advances in our understanding of the …

Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus

A Sreih, R Ezzeddine, L Leng, A LaChance… - Arthritis & …, 2011 - Wiley Online Library
Objective To study the effect of the innate cytokine macrophage migration inhibitory factor
(MIF) on the susceptibility and severity of systemic lupus erythematosus (SLE) in a …

hUC‐MSCs exosomal miR‐451 alleviated acute lung injury by modulating macrophage M2 polarization via regulating MIF‐PI3K‐AKT signaling pathway

J Liu, F Xing, Q Fu, B He, Z Jia, J Du, Y Li… - Environmental …, 2022 - Wiley Online Library
In the previous study, we have proved that exosomal miR‐451 from human umbilical cord
mesenchymal stem cells (hUC‐MSCs) attenuated burn‐induced acute lung injury (ALI) …

Macrophage CD74 contributes to MIF-induced pulmonary inflammation

K Takahashi, K Koga, HM Linge, Y Zhang, X Lin… - Respiratory …, 2009 - Springer
Background MIF is a critical mediator of the host defense, and is involved in both acute and
chronic responses in the lung. Neutralization of MIF reduces neutrophil accumulation into …

Prevention of oxygen‐induced inflammatory lung injury by caffeine in neonatal rats

S Endesfelder, E Strauß, I Bendix… - Oxidative medicine …, 2020 - Wiley Online Library
Background. Preterm birth implies an array of respiratory diseases including apnea of
prematurity and bronchopulmonary dysplasia (BPD). Caffeine has been introduced to treat …

MIF: a key player in cutaneous biology and wound healing

SC Gilliver, E Emmerson, J Bernhagen… - Experimental …, 2011 - Wiley Online Library
Owing to its implication in a range of pathological conditions, including asthma, rheumatoid
arthritis, atherosclerosis, inflammatory bowel disease and cancer, the pleiotropic cytokine …

Genetic heterogeneity and risk of acute respiratory distress syndrome

NJ Meyer, JD Christie - Seminars in respiratory and critical care …, 2013 - thieme-connect.com
Genetic variation explains some of the observed heterogeneity in patients' risk for
developing the acute respiratory distress syndrome (ARDS). Although the lack of extant …

Life without double-headed non-muscle myosin II motor proteins

V Betapudi - Frontiers in chemistry, 2014 - frontiersin.org
Non-muscle myosin II motor proteins (myosin IIA, myosin IIB, and myosin IIC) belong to a
class of molecular motor proteins that are known to transduce cellular free-energy into …

Genome-wide association study in African Americans with acute respiratory distress syndrome identifies the selectin P ligand gene as a risk factor

C Bime, N Pouladi, S Sammani, K Batai… - American journal of …, 2018 - atsjournals.org
Rationale: Genetic factors are involved in acute respiratory distress syndrome (ARDS)
susceptibility. Identification of novel candidate genes associated with increased risk and …