Current status and limitations of myocardial infarction large animal models in cardiovascular translational research
HS Shin, HH Shin, Y Shudo - Frontiers in bioengineering and …, 2021 - frontiersin.org
Establishing an appropriate disease model that mimics the complexities of human
cardiovascular disease is critical for evaluating the clinical efficacy and translation success …
cardiovascular disease is critical for evaluating the clinical efficacy and translation success …
The preclinical and clinical progress of cell sheet engineering in regenerative medicine
D Hu, X Li, J Li, P Tong, Z Li, G Lin, Y Sun… - Stem Cell Research & …, 2023 - Springer
Cell therapy is an accessible method for curing damaged organs or tissues. Yet, this
approach is limited by the delivery efficiency of cell suspension injection. Over recent years …
approach is limited by the delivery efficiency of cell suspension injection. Over recent years …
State-of-the-art methods for evaluation of angiogenesis and tissue vascularization: a scientific statement from the American Heart Association
M Simons, K Alitalo, BH Annex, HG Augustin… - Circulation …, 2015 - Am Heart Assoc
The American Heart Association makes every effort to avoid any actual or potential conflicts
of interest that may arise as a result of an outside relationship or a personal, professional, or …
of interest that may arise as a result of an outside relationship or a personal, professional, or …
Recombinant DTβ4-inspired porous 3D vascular graft enhanced antithrombogenicity and recruited circulating CD93+/CD34+ cells for endothelialization
W Xiao, W Chen, Y Wang, C Zhang, X Zhang… - Science …, 2022 - science.org
Matching material degradation with host remodeling, including endothelialization and
muscular remodeling, is important to vascular regeneration. We fabricated 3D PGS-PCL …
muscular remodeling, is important to vascular regeneration. We fabricated 3D PGS-PCL …
Angiogenic stem cell delivery platform to augment post-infarction neovasculature and reverse ventricular remodeling
Many cell-based therapies are challenged by the poor localization of introduced cells and
the use of biomaterial scaffolds with questionable biocompatibility or bio-functionality …
the use of biomaterial scaffolds with questionable biocompatibility or bio-functionality …
Regulation of endothelial progenitor cell functions in ischemic heart disease: new therapeutic targets for cardiac remodeling and repair
H Huang, W Huang - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Ischemic heart disease (IHD) is the leading cause of morbidity and mortality worldwide.
Ischemia and hypoxia following myocardial infarction (MI) cause subsequent cardiomyocyte …
Ischemia and hypoxia following myocardial infarction (MI) cause subsequent cardiomyocyte …
Natural heart regeneration in a neonatal rat myocardial infarction model
H Wang, MJ Paulsen, CE Hironaka, HS Shin, JM Farry… - Cells, 2020 - mdpi.com
Newborn mice and piglets exhibit natural heart regeneration after myocardial infarction (MI).
Discovering other mammals with this ability would provide evidence that neonatal cardiac …
Discovering other mammals with this ability would provide evidence that neonatal cardiac …
Incremental effect of coronary obstruction on myocardial microvascular dysfunction in type 2 diabetes mellitus patients evaluated by first-pass perfusion CMR study
J Wang, ZG Yang, YK Guo, Y Jiang, WF Yan… - Cardiovascular …, 2023 - Springer
Background Type 2 diabetes mellitus (T2DM) frequently coexists with obstructive coronary
artery disease (OCAD), which are at increased risk for cardiovascular morbidity and …
artery disease (OCAD), which are at increased risk for cardiovascular morbidity and …
Engineering biomimetic periosteum with β-TCP scaffolds to promote bone formation in calvarial defects of rats
D Zhang, P Gao, Q Li, J Li, X Li, X Liu, Y Kang… - Stem cell research & …, 2017 - Springer
Background There is a critical need for the management of large bone defects. The purpose
of this study was to engineer a biomimetic periosteum and to combine this with a …
of this study was to engineer a biomimetic periosteum and to combine this with a …
A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing …
JE Cohen, BP Purcell, JW MacArthur Jr… - Circulation: Heart …, 2014 - Am Heart Assoc
Background—Neuregulin-1β (NRG) is a member of the epidermal growth factor family
possessing a critical role in cardiomyocyte development and proliferation. Systemic …
possessing a critical role in cardiomyocyte development and proliferation. Systemic …