Compositions comprising first and second oligomers are pro vided wherein at least a portion
of the first oligomer is capable of hybridizing with at least a portion of the second oligomer, at …

Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene
Silencing in many organisms by a process known as RNA interference (RNAi). Using a …

Correspondence Address: MCDONNELL BOEHNEN HULBERT &(57) ABSTRACT
BERGHOFF The present invention concerns methods and reagents useful 300 SOUTH …

The present invention relates to a Drosophila in vitro system which was used to demonstrate
that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore …

2004-09-27 Assigned to SIRNA THERAPEUTICS, INC. reassignment SIRNA
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

The present invention provides modified oligomeric com pounds and compositions of
oligomeric compounds for use in the RNA interference pathway of gene modulation. The …

The present invention is related to a ribonucleic acid com prising a double stranded
structure whereby the double Stranded structure comprises a first strand and a second …

The present invention relates to a Drosophila in vitro System which was used to demonstrate
that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Further more …

0* CC (CC ([12*]) C) N ([8*]) C (= O) CCN ([3*]) C (= O) CCC (C) N ([5*]) C (= O) C1= CC= C
(N ([6*]) CC2= NC3= C (N= C2) N= C (C) NC3= O) C= C1 Chemical compound* CC (CC …

The present invention concerns methods and reagents useful in modulating hepatitis B virus
(HBV) gene expression in a variety of applications, including use in therapeutic, diag nostic …