[HTML][HTML] Appropriate therapeutic drug monitoring of biologic agents for patients with inflammatory bowel diseases

K Papamichael, AS Cheifetz, GY Melmed… - Clinical …, 2019 - Elsevier
Background & Aims Therapeutic drug monitoring (TDM) is widely available for biologic
therapies in patients with inflammatory bowel disease (IBD). We reviewed current data and …

Outcomes and strategies to support a treat-to-target approach in inflammatory bowel disease: a systematic review

JF Colombel, G D'haens, WJ Lee… - Journal of Crohn's …, 2020 - academic.oup.com
Abstract Background and Aims Management of Crohn's disease and ulcerative colitis has
typically relied upon treatment intensification driven by symptoms alone. However, a 'treat-to …

consensus statements on therapeutic drug monitoring of anti‐tumour necrosis factor therapy in inflammatory bowel diseases

N Mitrev, N Vande Casteele, CH Seow… - Alimentary …, 2017 - Wiley Online Library
Background Therapeutic drug monitoring (TDM) in inflammatory bowel disease (IBD)
patients receiving anti‐tumour necrosis factor (TNF) agents can help optimise outcomes …

The cost of inflammatory bowel disease in high-income settings: a Lancet Gastroenterology & Hepatology Commission

J Burisch, M Zhao, S Odes, P De Cruz… - The Lancet …, 2023 - thelancet.com
The cost of caring for patients with inflammatory bowel disease (IBD) continues to increase
worldwide. The cause is not only a steady increase in the prevalence of Crohn's disease …

Improved long-term outcomes of patients with inflammatory bowel disease receiving proactive compared with reactive monitoring of serum concentrations of infliximab

K Papamichael, KA Chachu, RK Vajravelu… - Clinical …, 2017 - Elsevier
Background & Aims Monitoring serum concentrations of tumor necrosis factor antagonists in
patients receiving these drugs as treatment for inflammatory bowel disease (IBD), also …

Infliximab in inflammatory bowel disease

K Papamichael, S Lin, M Moore… - … advances in chronic …, 2019 - journals.sagepub.com
Anti-tumor necrosis factor (TNF) therapy has revolutionized the medical treatment of the
inflammatory bowel diseases (IBD), Crohn's disease (CD), and ulcerative colitis. Twenty …

Clinical pharmacokinetic and pharmacodynamic considerations in the treatment of ulcerative colitis

SE Berends, AS Strik, M Löwenberg… - Clinical …, 2019 - Springer
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) of unknown etiology, probably
caused by a combination of genetic and environmental factors. The treatment of patients …

Proactive infliximab monitoring following reactive testing is associated with better clinical outcomes than reactive testing alone in patients with inflammatory bowel …

K Papamichael, RK Vajravelu… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims Reactive testing has emerged as the new standard of care
for managing loss of response to infliximab in inflammatory bowel disease [IBD]. Recent …

Optimizing treatment with TNF inhibitors in inflammatory bowel disease by monitoring drug levels and antidrug antibodies

C Steenholdt, K Bendtzen, J Brynskov… - Inflammatory bowel …, 2016 - academic.oup.com
Background Biological tumor necrosis factor (TNF) inhibitors have revolutionized the
treatment of inflammatory bowel disease and redefined treatment goals to include mucosal …

Use of anti-TNF drug levels to optimise patient management

K Papamichael, AS Cheifetz - Frontline gastroenterology, 2016 - fg.bmj.com
Anti-tumour necrosis factor (TNF) therapies, such as infliximab, adalimumab, certolizumab
pegol and golimumab, have been proven to be effective for the treatment of patients with …