Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …
Human serum albumin based nanodrug delivery systems: recent advances and future perspective
C Li, D Zhang, Y Pan, B Chen - Polymers, 2023 - mdpi.com
With the success of several clinical trials of products based on human serum albumin (HSA)
and the rapid development of nanotechnology, HSA-based nanodrug delivery systems …
and the rapid development of nanotechnology, HSA-based nanodrug delivery systems …
Radicals scavenging MOFs enabling targeting delivery of siRNA for rheumatoid arthritis therapy
L Guo, S Zhong, P Liu, M Guo, J Ding, W Zhou - Small, 2022 - Wiley Online Library
Macrophages play essential roles in the progression of rheumatoid arthritis (RA), which are
polarized into the pro‐inflammatory M1 phenotype with significant oxidative stress and …
polarized into the pro‐inflammatory M1 phenotype with significant oxidative stress and …
Multifunctional Janus nanoplatform for efficiently synergistic theranostics of rheumatoid arthritis
Progress has been made in the application of nanomedicine in rheumatoid arthritis (RA)
treatment. However, the whole process of monitoring and treatment of RA remains a …
treatment. However, the whole process of monitoring and treatment of RA remains a …
Spatiotemporal catalytic nanozymes microneedle patches with opposite properties for wound management
J Shan, X Zhang, L Wang, Y Zhao - Small, 2023 - Wiley Online Library
Reactive oxygen species (ROS)‐mediated biological catalysis involves serial programmed
enzymatic reactions and plays an important part against infectious diseases; while the …
enzymatic reactions and plays an important part against infectious diseases; while the …
A multifunctional nanoaggregate‐based system for detection of rheumatoid arthritis via optoacoustic/NIR‐II fluorescent imaging and therapy via inhibiting JAK‐STAT …
J Chen, L Chen, Z She, F Zeng, S Wu - Aggregate, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is a debilitating autoimmune disease that causes chronic pain and
serious complications, presenting a significant challenge to treat. Promising approaches for …
serious complications, presenting a significant challenge to treat. Promising approaches for …
Multiscale structural design of MnO2@GO superoxide dismutase nanozyme for protection against antioxidant damage
Y Yu, Y Zhang, Y Wang, W Chen, Z Guo, N Song… - Nano Research, 2023 - Springer
Rational design of metallic active sites and its microenvironment is critical for constructing
superoxide dismutase (SOD) nanozymes. Here, we reported a novel SOD nanozyme …
superoxide dismutase (SOD) nanozymes. Here, we reported a novel SOD nanozyme …
Macrophage reprogramming via targeted ROS scavenging and COX-2 downregulation for alleviating inflammation
X Luo, H Xiong, Y Jiang, Y Fan, C Zuo… - Bioconjugate …, 2023 - ACS Publications
Inflammation-related diseases affect large populations of people in the world and cause
substantial healthcare burdens, which results in significant costs in time, material, and labor …
substantial healthcare burdens, which results in significant costs in time, material, and labor …
Targeted co-delivery biomimetic nanoparticles reverse macrophage polarization for enhanced rheumatoid arthritis therapy
X Zheng, X Yu, C Wang, Y Liu, M Jia, F Lei, J Tian… - Drug Delivery, 2022 - Taylor & Francis
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, which is characterized
by synovial inflammation and autoimmunity. The main cause of the disease is the imbalance …
by synovial inflammation and autoimmunity. The main cause of the disease is the imbalance …
Acupoint nanocomposite hydrogel for simulation of acupuncture and targeted delivery of triptolide against rheumatoid arthritis
S Ren, H Liu, X Wang, J Bi, S Lu, C Zhu, H Li… - Journal of …, 2021 - Springer
Background Attenuating inflammatory response and relieving pain are two therapeutic
therapeutical goals for rheumatoid arthritis (RA). Anti-inflammatory and analgesic drugs are …
therapeutical goals for rheumatoid arthritis (RA). Anti-inflammatory and analgesic drugs are …