Our understanding of the functions of the IL-1 superfamily cytokine and damage-associated
molecular pattern IL-33 continues to evolve with our understanding of homeostasis and …

There is a growing interest in using natural medicines to treat stroke as the leading cause of
disability worldwide. Especially plant-derived natural medicines have multiple beneficial …

Among age-related diseases, cardiovascular and cerebrovascular diseases are major
causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age …

Abstract Interleukin 33 (IL-33), which is expressed by several immune cell types, endothelial
and epithelial cells, and fibroblasts, is a cytokine of the IL-1 family that acts both intra-and …

Background Acute ischemic stroke (AIS) is the most common type of cerebrovascular
disease and is a leading cause of disability and death worldwide. Recently, a study …

According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

Interleukin-33 (IL-33), a member of the IL-1 cytokine family, is involved in various diseases.
IL-33 exerts its effects via its heterodimeric receptor complex, which comprises suppression …

Interleukin-33 (IL-33) is a well-recognized immunomodulatory cytokine which plays critical
roles in tissue function and immune-mediated diseases. The abundant expression of IL-33 …

Interleukin (IL)-33 and its unique receptor, ST2, play a pivotal role in the immune response
to infection and stress. However, there have been conflicting reports of the role of IL-33 in …

The inflammatory response is an unavoidable process and contributes to the destruction of
cerebral tissue during the acute ischemic stroke (AIS) phase and has not been addressed …