Radiotheranostics in oncology: making precision medicine possible

EO Aboagye, TD Barwick… - CA: a cancer journal for …, 2023 - Wiley Online Library
A quintessential setting for precision medicine, theranostics refers to a rapidly evolving field
of medicine in which disease is diagnosed followed by treatment of disease‐positive …

The effect of hypoxia on the expression of CXC chemokines and CXC chemokine receptors—a review of literature

J Korbecki, K Kojder, P Kapczuk, P Kupnicka… - International journal of …, 2021 - mdpi.com
Hypoxia is an integral component of the tumor microenvironment. Either as chronic or
cycling hypoxia, it exerts a similar effect on cancer processes by activating hypoxia-inducible …

Radiotheranostics: a roadmap for future development

K Herrmann, M Schwaiger, JS Lewis… - The Lancet …, 2020 - thelancet.com
Radiotheranostics, injectable radiopharmaceuticals with antitumour effects, have seen rapid
development over the past decade. Although some formulations are already approved for …

Role of 18F-FDG PET/CT in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International …

M Cavo, E Terpos, C Nanni, P Moreau… - The lancet …, 2017 - thelancet.com
Summary The International Myeloma Working Group consensus aimed to provide
recommendations for the optimal use of 18 fluorodeoxyglucose (18 F-FDG) PET/CT in …

Imaging of CXC motif chemokine receptor 4 expression in 690 patients with solid or hematologic neoplasms using 68Ga-pentixafor PET

AK Buck, A Haug, N Dreher, A Lambertini… - Journal of Nuclear …, 2022 - Soc Nuclear Med
In recent years, molecular imaging addressing the CXC motif chemokine receptor 4
(CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess …

[HTML][HTML] [68Ga] Pentixafor-PET/CT for imaging of chemokine receptor CXCR4 expression in multiple myeloma-Comparison to [18F] FDG and laboratory values

C Lapa, M Schreder, A Schirbel, S Samnick… - Theranostics, 2017 - ncbi.nlm.nih.gov
Abstract Chemokine (CXC motif) receptor 4 (CXCR4) is a key factor for tumor growth and
metastasis in several types of human cancer including multiple myeloma (MM). Proof-of …

Glu-ureido–based inhibitors of prostate-specific membrane antigen: lessons learned during the development of a novel class of low-molecular-weight theranostic …

K Kopka, M Benešová, C Bařinka… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In recent years, several radioligands targeting prostate-specific membrane antigen (PSMA)
have been clinically introduced as a new class of theranostic radiopharmaceuticals for the …

Targeting CXCR4 in AML and all

D Cancilla, MP Rettig, JF DiPersio - Frontiers in oncology, 2020 - frontiersin.org
The interaction of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL)
blasts with the bone marrow microenvironment regulates self-renewal, growth signaling, as …

Future cancer research priorities in the USA: a Lancet Oncology Commission

EM Jaffee, C Van Dang, DB Agus… - The Lancet …, 2017 - thelancet.com
We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …

CXCR4-directed theranostics in oncology and inflammation

M Kircher, P Herhaus, M Schottelius, AK Buck… - Annals of nuclear …, 2018 - Springer
Given its prominent role in inflammation and cancer biology, the CXC motif chemokine
receptor 4 (CXCR4) has gained a lot of attention in the recent years. This review gives a …