Simple Summary Today, the classification of acute myeloid leukemia is mainly based on
genetic aberrations found in leukemic cells. Classifying this disease is necessary for exact …

Abstract Optical Genome Mapping (OGM) is rapidly emerging as an exciting cytogenomic
technology both for research and clinical purposes. In the last 2 years alone, multiple studies …

Simple Summary In many countries, the standard-of-care cytogenetic analysis of chronic
lymphocytic leukemia (CLL) is based on the fluorescence in situ hybridization (FISH) …

Simple Summary Myeloma is a hematological cancer characterized by numerous genetic
abnormalities currently identified using fluorescent in situ hybridization (FISH). However …

Optical genome mapping (OGM) is a new genome-wide technology that can reveal both
structural genomic variations (SVs) and copy number variations (CNVs) in a single assay …

Simple Summary Acute leukemia is a rare but severe disease for which genetic
characterization allows diagnostic and prognostic classification and therapeutic …

The mutational landscape of B-cell precursor acute lymphoblastic leukemia (BCP-ALL), the
most common pediatric cancer, is not fully described partially because commonly applied …

Chromosomal abnormalities are frequent in chronic lymphocytic leukemia (CLL), and most
have prognostic value. In addition to the four well-known abnormalities (13q, 11q and 17p …

Genomic characterization is an essential part of the clinical management of hematological
malignancies for diagnostic, prognostic and therapeutic purposes. Although CBA and FISH …

Chronic lymphocytic leukaemia (CLL) is a haematological malignancy characterised by the
accumulation of monoclonal mature B lymphocytes (positive for CD5+ and CD23+) in …