Breathing movements in mammals are driven by rhythmic neural activity generated within
spatially and functionally organized brainstem neural circuits comprising the respiratory …

Breathing is an essential behavior that presents a unique opportunity to understand how the
nervous system functions normally, how it balances inherent robustness with a highly …

Obesity is a major public health issue worldwide. Understanding how the brain controls
appetite offers promising inroads toward new therapies for obesity. Peptide YY (PYY) and …

Pontine respiratory nuclei provide synaptic input to medullary rhythmogenic circuits to shape
and adapt the breathing pattern. An understanding of this statement depends on …

While motor cortical circuits contain information related to specific movement parameters,
long-range inputs also have a critical role in action execution,. Thalamic projections can …

The brainstem is directly involved in controlling blood pressure, respiration, sleep/wake
cycles, pain modulation, motor, and cardiac output. As such it is of significant basic science …

The human brainstem plays a central role in connecting the cerebrum, the cerebellum and
the spinal cord to one another, hosting relay nuclei for afferent and efferent signaling, and …

The early detection of stimuli signalling threat to an organism is a crucial evolutionary
advantage. For example, the perception of aversive bodily sensations such as dyspnea and …

Despite recent advances in understanding how respiration affects neural signalling to
influence perception, cognition, and behaviour, it is yet unclear to what extent breathing …

The pre-Bötzinger complex has been identified as an essential part of the medullary
respiratory network in mammals. Although well described in experimental animals, its …