[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives
H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
Lipid nanoparticles for nucleic acid delivery: Current perspectives
E Samaridou, J Heyes, P Lutwyche - Advanced drug delivery reviews, 2020 - Elsevier
Nucleic Acid (NA) based therapeutics are poised to disrupt modern medicine and augment
traditional pharmaceutics in a meaningful way. However, a key challenge to advancing NA …
traditional pharmaceutics in a meaningful way. However, a key challenge to advancing NA …
[HTML][HTML] Hyaluronic acid and albumin based nanoparticles for drug delivery
C Lei, XR Liu, QB Chen, Y Li, JL Zhou, LY Zhou… - Journal of Controlled …, 2021 - Elsevier
Albumin, a multifunctional protein, is widely used to prepare nanocarriers. Hyaluronic acid
(HA) is a natural glycosaminoglycan that can specifically bind receptors, such as cluster of …
(HA) is a natural glycosaminoglycan that can specifically bind receptors, such as cluster of …
Drug delivery to the posterior segment of the eye: biopharmaceutic and pharmacokinetic considerations
R Varela-Fernández, V Díaz-Tomé… - Pharmaceutics, 2020 - mdpi.com
The treatment of the posterior-segment ocular diseases, such as age-related eye diseases
(AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the …
(AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the …
[HTML][HTML] Microneedles for advanced ocular drug delivery
In the field of ocular drug delivery, topical delivery remains the most common treatment
option for managing anterior segment diseases, while intraocular injections are the current …
option for managing anterior segment diseases, while intraocular injections are the current …
[HTML][HTML] Polymeric micelles for ocular drug delivery: From structural frameworks to recent preclinical studies
Effective intraocular drug delivery poses a major challenge due to the presence of various
elimination mechanisms and physiological barriers that result in low ocular bioavailability …
elimination mechanisms and physiological barriers that result in low ocular bioavailability …
Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …
tissues continues to be a key challenge for formulation scientists. Various attempts are …
Microneedle, bio-microneedle and bio-inspired microneedle: A review
G Ma, C Wu - Journal of Controlled Release, 2017 - Elsevier
Microneedles (MNs) are micro-scale needles used for drug delivery and other targets. Micro-
scale size endows them with many advantages over hypodermic needles, including …
scale size endows them with many advantages over hypodermic needles, including …
Hydrogel biomaterials for application in ocular drug delivery
CR Lynch, PPD Kondiah, YE Choonara… - … in bioengineering and …, 2020 - frontiersin.org
There are many challenges involved in ocular drug delivery. These are a result of the many
tissue barriers and defense mechanisms that are present with the eye; such as the cornea …
tissue barriers and defense mechanisms that are present with the eye; such as the cornea …
[HTML][HTML] A review on recent drug delivery systems for posterior segment of eye
K Nayak, M Misra - Biomedicine & pharmacotherapy, 2018 - Elsevier
Eye is the unique sense organ with complex and sophisticated anatomy and physiology.
Being most instrumental for vision, it is secured by varied protective barriers; ranging from …
Being most instrumental for vision, it is secured by varied protective barriers; ranging from …