Epigenetic changes and assisted reproductive technologies

S Mani, J Ghosh, C Coutifaris, C Sapienza, M Mainigi - Epigenetics, 2020 - Taylor & Francis
ABSTRACT Children conceived by Assisted Reproductive Technologies (ART) are at
moderately increased risk for a number of undesirable outcomes, including low birth weight …

DNA methylation profiles after ART during human lifespan: a systematic review and meta-analysis

J Barberet, B Ducreux, M Guilleman… - Human …, 2022 - academic.oup.com
BACKGROUND The many manipulations and processes used in ART coincide with the
timing of epigenetic reprogramming and imprinting during female gametogenesis and pre …

Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood

B Novakovic, S Lewis, J Halliday, J Kennedy… - Nature …, 2019 - nature.com
More than 7 million individuals have been conceived by Assisted Reproductive
Technologies (ART) and there is clear evidence that ART is associated with a range of …

Antioxidants improve IVF outcome and subsequent embryo development in the mouse

T Truong, DK Gardner - Human Reproduction, 2017 - academic.oup.com
STUDY QUESTION What is the effect of a combination of three antioxidants (Acetyl-L-
Carnitine, N-Acetyl-L-Cysteine and α-Lipoic Acid), present in IVF medium during mouse …

Impact of the IVF laboratory environment on human preimplantation embryo phenotype

DK Gardner, RL Kelley - Journal of Developmental Origins of Health …, 2017 - cambridge.org
The phenotype of the human embryo conceived through in vitro fertilization (IVF), that is its
morphology, developmental kinetics, physiology and metabolism, can be affected by …

DNA methylation in embryo development: epigenetic impact of ART (assisted reproductive technologies)

S Canovas, PJ Ross, G Kelsey, P Coy - Bioessays, 2017 - Wiley Online Library
DNA methylation can be considered a component of epigenetic memory with a critical role
during embryo development, and which undergoes dramatic reprogramming after …

Embryo responses to stress induced by assisted reproductive technologies

P Ramos‐Ibeas, S Heras… - Molecular …, 2019 - Wiley Online Library
Assisted reproductive technology (ART) has led to the birth of millions of babies. In cattle,
thousands of embryos are produced annually. However, since the introduction and …

Contemporary use of ICSI and epigenetic risks to future generations

R Sciorio, SC Esteves - Journal of Clinical Medicine, 2022 - mdpi.com
Since the birth of Louise Brown in 1978 via IVF, reproductive specialists have acquired
enormous knowledge and refined several procedures, which are nowadays applied in …

Genetics and epigenetics of infertility and treatments on outcomes

MD Pisarska, JL Chan, K Lawrenson… - The Journal of …, 2019 - academic.oup.com
Context Infertility affects 10% of the reproductive-age population. Even the most successful
treatments such as assisted reproductive technologies still result in failed implantation. In …

Superovulation alters the expression of endometrial genes critical to tissue remodeling and placentation

S Senapati, F Wang, T Ord, C Coutifaris, R Feng… - Journal of assisted …, 2018 - Springer
Purpose Epidemiologic data suggest that in vitro fertilization (IVF) is associated with an
increased risk of disorders of placentation including preeclampsia and fetal growth …