Epigenetic changes and assisted reproductive technologies
ABSTRACT Children conceived by Assisted Reproductive Technologies (ART) are at
moderately increased risk for a number of undesirable outcomes, including low birth weight …
moderately increased risk for a number of undesirable outcomes, including low birth weight …
DNA methylation profiles after ART during human lifespan: a systematic review and meta-analysis
J Barberet, B Ducreux, M Guilleman… - Human …, 2022 - academic.oup.com
BACKGROUND The many manipulations and processes used in ART coincide with the
timing of epigenetic reprogramming and imprinting during female gametogenesis and pre …
timing of epigenetic reprogramming and imprinting during female gametogenesis and pre …
Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
B Novakovic, S Lewis, J Halliday, J Kennedy… - Nature …, 2019 - nature.com
More than 7 million individuals have been conceived by Assisted Reproductive
Technologies (ART) and there is clear evidence that ART is associated with a range of …
Technologies (ART) and there is clear evidence that ART is associated with a range of …
Antioxidants improve IVF outcome and subsequent embryo development in the mouse
T Truong, DK Gardner - Human Reproduction, 2017 - academic.oup.com
STUDY QUESTION What is the effect of a combination of three antioxidants (Acetyl-L-
Carnitine, N-Acetyl-L-Cysteine and α-Lipoic Acid), present in IVF medium during mouse …
Carnitine, N-Acetyl-L-Cysteine and α-Lipoic Acid), present in IVF medium during mouse …
Impact of the IVF laboratory environment on human preimplantation embryo phenotype
DK Gardner, RL Kelley - Journal of Developmental Origins of Health …, 2017 - cambridge.org
The phenotype of the human embryo conceived through in vitro fertilization (IVF), that is its
morphology, developmental kinetics, physiology and metabolism, can be affected by …
morphology, developmental kinetics, physiology and metabolism, can be affected by …
DNA methylation in embryo development: epigenetic impact of ART (assisted reproductive technologies)
DNA methylation can be considered a component of epigenetic memory with a critical role
during embryo development, and which undergoes dramatic reprogramming after …
during embryo development, and which undergoes dramatic reprogramming after …
Embryo responses to stress induced by assisted reproductive technologies
P Ramos‐Ibeas, S Heras… - Molecular …, 2019 - Wiley Online Library
Assisted reproductive technology (ART) has led to the birth of millions of babies. In cattle,
thousands of embryos are produced annually. However, since the introduction and …
thousands of embryos are produced annually. However, since the introduction and …
Contemporary use of ICSI and epigenetic risks to future generations
R Sciorio, SC Esteves - Journal of Clinical Medicine, 2022 - mdpi.com
Since the birth of Louise Brown in 1978 via IVF, reproductive specialists have acquired
enormous knowledge and refined several procedures, which are nowadays applied in …
enormous knowledge and refined several procedures, which are nowadays applied in …
Genetics and epigenetics of infertility and treatments on outcomes
MD Pisarska, JL Chan, K Lawrenson… - The Journal of …, 2019 - academic.oup.com
Context Infertility affects 10% of the reproductive-age population. Even the most successful
treatments such as assisted reproductive technologies still result in failed implantation. In …
treatments such as assisted reproductive technologies still result in failed implantation. In …
Superovulation alters the expression of endometrial genes critical to tissue remodeling and placentation
Purpose Epidemiologic data suggest that in vitro fertilization (IVF) is associated with an
increased risk of disorders of placentation including preeclampsia and fetal growth …
increased risk of disorders of placentation including preeclampsia and fetal growth …