[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis

W Jia, Y Li, KCP Cheung, X Zheng - Science China Life Sciences, 2024 - Springer
Bile acids (BAs) play a crucial role in nutrient absorption and act as key regulators of lipid
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …

[HTML][HTML] Galectin-3 regulates microglial activation and promotes inflammation through TLR4/MyD88/NF-kB in experimental autoimmune uveitis

Y Liu, C Zhao, J Meng, N Li, Z Xu, X Liu, S Hou - Clinical Immunology, 2022 - Elsevier
Galectin-3, an attractive molecule of innate immunity, has been reported to be involved in
the neuroinflammatory diseases. However, the role of Galectin-3 in autoimmune uveitis is …

[HTML][HTML] Vaccine-associated uveitis after COVID-19 vaccination: vaccine adverse event reporting system database analysis

RB Singh, UPS Parmar, F Kahale, A Agarwal, E Tsui - Ophthalmology, 2023 - Elsevier
Purpose To assess the risk of vaccine-associated uveitis (VAU) after severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and evaluate uveitis onset …

Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis

Z Zhong, G Su, A Kijlstra, P Yang - Progress in retinal and eye research, 2021 - Elsevier
Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy

J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and
related conditions, pose considerable challenges to effective management and treatment …

Circulating Calprotectin (cCLP) in autoimmune diseases

M Manfredi, L Van Hoovels, M Benucci, R De Luca… - Autoimmunity …, 2023 - Elsevier
Background and aim Calprotectin (CLP) is a heterodimeric complex formed by two S100
proteins (S100A8/A9), which plays a pivotal role in innate immunity. Due to its intrinsic …

Epidemiology and risk factors in non-infectious uveitis: a systematic review

KA Joltikov, AM Lobo-Chan - Frontiers in Medicine, 2021 - frontiersin.org
Purpose: Non-infectious uveitis is a leading cause of vision loss in the developed world. The
purpose of this systematic review is to investigate the epidemiology and risk factors of non …

Ocular drug delivery to the anterior segment using nanocarriers: A mucoadhesive/mucopenetrative perspective

RS Dave, TC Goostrey, M Ziolkowska… - Journal of Controlled …, 2021 - Elsevier
There is a growing demand for effective treatments for ocular conditions that improve patient
compliance and reduce side-effects. While methods such as implants and injections have …

Targeting the gut–eye axis: An emerging strategy to face ocular diseases

LIM Campagnoli, A Varesi, A Barbieri… - International Journal of …, 2023 - mdpi.com
The human microbiota refers to a large variety of microorganisms (bacteria, viruses, and
fungi) that live in different human body sites, including the gut, oral cavity, skin, and eyes. In …