Recently Discovered Secondary Metabolites from Streptomyces Species

HJ Lacey, PJ Rutledge - Molecules, 2022 - mdpi.com
The Streptomyces genus has been a rich source of bioactive natural products, medicinal
chemicals, and novel drug leads for three-quarters of a century. Yet studies suggest that the …

Bioactive metabolites from terrestrial and marine actinomycetes

C Ngamcharungchit, N Chaimusik, W Panbangred… - Molecules, 2023 - mdpi.com
Actinomycetes inhabit both terrestrial and marine ecosystems and are highly proficient in
producing a wide range of natural products with diverse biological functions, including …

An insight into the recent developments in anti-infective potential of indole and associated hybrids

BS Mathada, SB Somappa - Journal of Molecular Structure, 2022 - Elsevier
Prevention, accurate diagnosis, and effective treatment of infections are the main challenges
in the overall management of infectious diseases. The best example is the ongoing SARs …

Bacterial pathogens: threat or treat (a review on bioactive natural products from bacterial pathogens)

F Maglangit, Y Yu, H Deng - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to the second quarter of 2020 Threat or treat? While pathogenic bacteria pose
significant threats, they also represent a huge reservoir of potential pharmaceuticals to treat …

Screening of a Novel Fibrinolytic Enzyme-Producing Streptomyces from a Hyper-Arid Area and Optimization of Its Fibrinolytic Enzyme Production

Z He, Y Sun, M Chu, J Zhu, Y Zhang, Q Tang, G Osman… - Fermentation, 2023 - mdpi.com
Fibrinolytic enzymes are a kind of proteolytic enzymes that can hydrolyze fibrin and dissolve
blood clots. They could be used as a therapeutic agent for treating thrombosis. It is important …

Streptomyces sp. VITGV100: an endophyte from Lycopersicon esculentum as new source of indole type compounds

P Veilumuthu, T Nagarajan, S Sasikumar, R Siva… - Biochemical Systematics …, 2022 - Elsevier
Streptomyces spp. Produce a wide range of antimicrobial, anticancer, antioxidant,
immunosuppressant, antiviral, and antimalarial compounds. Their genome harbour a vast …

Unleashing the potential of microbial natural products in drug discovery: focusing on streptomyces as antimicrobials goldmine

H Bansal, RK Singla, S Behzad… - Current Topics in …, 2021 - ingentaconnect.com
The natural product specialized metabolites produced by microbes and plants are the
backbone of our current drugs. Ironically, we are in a golden age of understanding natural …

Deletion of the accramycin pathway-specific regulatory gene accJ activates the production of unrelated polyketide metabolites

F Maglangit, K Kyeremeh, H Deng - Natural Product Research, 2023 - Taylor & Francis
The manipulation of regulatory genes has been employed to awaken cryptic metabolites in
Streptomyces. Of particular interest in recent years is the effect of disruption of a pathway …

Indole-3-carboxylic acid from the endophytic fungus Lasiodiplodia pseudotheobromae LPS-1 as a synergist enhancing the antagonism of jasmonic acid against …

Y Que, D Huang, S Gong, X Zhang, B Yuan… - Frontiers in Cellular …, 2022 - frontiersin.org
The discovery of natural bioactive compounds from endophytes or medicinal plants against
plant diseases is an attractive option for reducing the use of chemical fungicides. In this …

In vitro antimicrobial and antimalarial screening of a crude extract of Streptomyces sp. AB8 isolated from Lapindo Mud Volcano Area, Sidoarjo, Indonesia

A Arifiyanto, E Setyaningrum, N Nukmal… - Biodiversitas Journal of …, 2021 - smujo.id
Arifiyanto A, Setyaningrum E, Nukmal N, Aeny TN. 2021. Short Communication: In vitro
antimicrobial and antimalarial screening of a crude extract of Streptomyces sp. AB8 isolated …