Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

The previous decade has seen a rapid increase in microglial studies on pain, with a unique
focus on microgliosis in the spinal cord after nerve injury and neuropathic pain. Numerous …

Practitioners of ancient societies from the time of Hippocrates and earlier recognized and
treated the signs of inflammation, heat, redness, swelling, and pain with agents that block or …

Traumatic brain injury (TBI) contributes a major cause of death, disability, and mental health
disorders. Most TBI patients suffer long-term post-traumatic stress disorder, cognitive …

For several decades, there has been considerable interest in marine‐derived long chain n‐3
fatty acids (n‐3 LCPUFAs) due to their outstanding health benefits. n‐3 LCPUFAs can be …

The acute inflammatory response is host-protective to contain foreign invaders. Many of
today's pharmacopeia that block pro-inflammatory chemical mediators can cause serious …

The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain
containing 3 (NLRP3) inflammasome-mediated inflammatory response has emerged as a …

Inflammation has been identified as one of the main pathophysiological mechanisms
underlying neuropsychiatric and neurodegenerative disorders. Despite the role of …

Summary Programmed death protein 1 (PD-1) and its ligand PD-L1 constitute an immune
checkpoint pathway. We report that neuronal PD-1 signaling regulates learning/memory in …

In the past few decades, as a result of their anti-inflammatory properties, n-3 long chain
polyunsaturated fatty acids (n-3 LC-PUFAs), have gained greater importance in the …