DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

The importance of β-adrenergic signaling in the heart has been well documented, but it is
only more recently that we have begun to understand the importance of this signaling …

Mesenchymal responses are an essential aspect of tissue repair. Failure to terminate this
repair process correctly, however, results in fibrosis and organ dysfunction. Therapies that …

Exercise provides numerous salutary effects, but our understanding of how these occur is
limited. To gain a clearer picture of exercise-induced metabolic responses, we have …

The NAD+-dependent deacetylase SIRT1 is an evolutionarily conserved metabolic sensor of
the Sirtuin family that mediates homeostatic responses to certain physiological stresses such …

The nuclear hormone receptor (NR) superfamily includes the orphan NR4A subgroup,
comprised of Nur77 (NR4A1), Nurr1 (NR4A2) and NOR-1 (NR4A3). These NRs are …

Numerous members of the nuclear hormone receptor (NR) superfamily have been
demonstrated to regulate metabolic function in a cell-and tissue-specific manner. This …

Background: Takotsubo syndrome (TTS) is characterized by an acute left ventricular
dysfunction and is associated with life-threating complications in the acute phase. The …

The Nr4a family of nuclear hormone receptors is composed of three members—
Nr4a1/Nur77, Nr4a2/Nurr1 and Nr4a3/Nor1. While currently defined as ligandless, these …

Members of the nuclear hormone receptor superfamily, including the peroxisome proliferator–
activated receptor and the liver X receptor subfamilies, orchestrate transcriptional networks …