Molecular biomarkers in multiple sclerosis
T Ziemssen, K Akgün, W Brück - Journal of neuroinflammation, 2019 - Springer
Multiple sclerosis (MS) is an inflammatory-neurodegenerative disease of the central nervous
system presenting with significant inter-and intraindividual heterogeneity. However, the …
system presenting with significant inter-and intraindividual heterogeneity. However, the …
2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3–LBA/cell-based assays …
L Stevenson, S Richards, R Pillutla, A Torri… - Bioanalysis, 2018 - Taylor & Francis
Abstract The 2018 12th Workshop on Recent Issues in Bioanalysis took place in
Philadelphia, PA, USA on April 9–13, 2018 with an attendance of over 900 representatives …
Philadelphia, PA, USA on April 9–13, 2018 with an attendance of over 900 representatives …
Recommendations on qPCR/ddPCR assay validation by GCC
M Wissel, M Poirier, C Satterwhite, J Lin, R Islam… - Bioanalysis, 2022 - Taylor & Francis
Gene therapy, cell therapy and vaccine research have led to an increased use of
qPCR/ddPCR in bioanalytical laboratories. CROs are progressively undertaking the …
qPCR/ddPCR in bioanalytical laboratories. CROs are progressively undertaking the …
2017 White Paper on recent issues in bioanalysis: a global perspective on immunogenicity guidelines & biomarker assay performance (Part 3–LBA: immunogenicity …
S Gupta, S Richards, L Amaravadi, S Piccoli… - Bioanalysis, 2017 - Taylor & Francis
The 2017 11th Workshop on Recent Issues in Bioanalysis took place in Los
Angeles/Universal City, California, on 3–7 April 2017 with participation of close to 750 …
Angeles/Universal City, California, on 3–7 April 2017 with participation of close to 750 …
2013 White Paper on Recent Issues in Bioanalysis: 'Hybrid' – The Best of LBA and LCMS
L Stevenson, F Garofolo, B DeSilva, I Dumont… - Bioanalysis, 2013 - Taylor & Francis
The 2013 7th Workshop on Recent Issues in Bioanalysis was held in Long Beach,
California, USA, where close to 500 professionals from pharmaceutical and …
California, USA, where close to 500 professionals from pharmaceutical and …
Parallelism experiments to evaluate matrix effects, selectivity and sensitivity in ligand-binding assay method development: pros and cons
J Tu, P Bennett - Bioanalysis, 2017 - Taylor & Francis
Parallelism is an essential experiment characterizing relative accuracy for a ligand-binding
assay (LBA). By assessing the effects of dilution on the quantitation of endogenous analyte …
assay (LBA). By assessing the effects of dilution on the quantitation of endogenous analyte …
Evaluation of electrolyte element composition in human tissue by laser-induced breakdown spectroscopy (LIBS)
P Winnand, KO Boernsen, G Bodurov, M Lammert… - Scientific Reports, 2022 - nature.com
Laser-induced breakdown spectroscopy (LIBS) enables the direct measurement of cell
electrolyte concentrations. The utility of LIBS spectra in biomarker studies is limited because …
electrolyte concentrations. The utility of LIBS spectra in biomarker studies is limited because …
Validation of sputum biomarker immunoassays and cytokine expression profiles in COPD
A Mulvanny, C Pattwell, A Beech, T Southworth… - Biomedicines, 2022 - mdpi.com
Immunoassays are commonly used to assess airway inflammation in sputum samples from
chronic obstructive pulmonary disease (COPD) patients. However, assay performance and …
chronic obstructive pulmonary disease (COPD) patients. However, assay performance and …
2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV):(Part 3–LBA, biomarkers and immunogenicity)
S Richards, L Amaravadi, R Pillutla, H Birnboeck… - Bioanalysis, 2016 - Taylor & Francis
The 2016 10th Workshop on Recent Issues in Bioanalysis (10th WRIB) took place in
Orlando, Florida with participation of close to 700 professionals from pharmaceutical …
Orlando, Florida with participation of close to 700 professionals from pharmaceutical …
Biomarker assay validation by mass spectrometry
C Fernández-Metzler, B Ackermann, F Garofolo… - The AAPS Journal, 2022 - Springer
Decades of discussion and publication have gone into the guidance from the scientific
community and the regulatory agencies on the use and validation of pharmacokinetic and …
community and the regulatory agencies on the use and validation of pharmacokinetic and …