Plant secondary metabolites (SMs) play important roles in plant survival and in creating
ecological connections between other species. In addition to providing a variety of valuable …

The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

Melatonin is an ancient antioxidant. After its initial development in bacteria, it has been
retained throughout evolution such that it may be or may have been present in every species …

Melatonin, along with its metabolites, have long been known to significantly reduce the
oxidative stress burden of aging cells or cells exposed to toxins. Oxidative damage is a …

Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine), an indoleamine produced in many
organs including the pineal gland, was initially characterized as a hormone primarily …

Free radicals generated within subcellular compartments damage macromolecules which
lead to severe structural changes and functional alterations of cellular organelles. A …

Melatonin is a naturally occurring molecule secreted by the pineal gland and known as a
gatekeeper of circadian clocks. Mounting evidence indicates that melatonin, employing …

Acute pancreatitis (AP) is an inflammatory disease of highly variable severity, ranging from
mild cases with low mortality to severe cases with high mortality. Numerous biomarkers have …

The discovery of melatonin and its derivatives as antioxidants has stimulated a very large
number of studies which have, virtually uniformly, documented the ability of these molecules …

The classic theories of aging such as the free radical theory, including its mitochondria‐
related versions, have largely focused on a few specific processes of senescence …