[HTML][HTML] Does vitamin C influence neurodegenerative diseases and psychiatric disorders?

J Kocot, D Luchowska-Kocot, M Kiełczykowska, I Musik… - Nutrients, 2017 - mdpi.com
Vitamin C (Vit C) is considered to be a vital antioxidant molecule in the brain. Intracellular Vit
C helps maintain integrity and function of several processes in the central nervous system …

The role of vitamin C in stress-related disorders

B Moritz, AE Schmitz, ALS Rodrigues, AL Dafre… - The Journal of …, 2020 - Elsevier
Stress-related disorders, such as depression and anxiety, present marked deficits in
behavioral and cognitive functions related to reward. These are highly prevalent disabling …

[HTML][HTML] Effects of chronic exposure of naturally weathered microplastics on oxidative stress level, behaviour, and mitochondrial function of adult zebrafish (Danio rerio …

L Félix, P Carreira, F Peixoto - Chemosphere, 2023 - Elsevier
Microplastics (MPs) are a big and growing environmental concern, with studies showing
sublethal to acute biological impacts on typical aquatic organisms. However, little is known …

[HTML][HTML] Nano-TiO2 aggravates bioaccumulation and developmental neurotoxicity of difenoconazole in zebrafish larvae via oxidative stress and apoptosis: Protective …

R Zhu, C Liu, J Wang, L Zou, F Yang, X Chi… - … and Environmental Safety, 2023 - Elsevier
Titanium dioxide nanoparticles (n-TiO 2) could enhance the bioavailability and toxicity of
coexisting organic contaminants in the aquatic environment. This study attempted to …

[HTML][HTML] Vitamin C mitigates oxidative stress and behavioral impairments induced by deltamethrin and lead toxicity in zebrafish

E Paduraru, EI Flocea, CC Lazado, IA Simionov… - International Journal of …, 2021 - mdpi.com
Environmental contamination from toxic metals and pesticides is an issue of great concern
due to their harmful effects to human health and the ecosystems. In this framework, we …

Neurobiology of vitamin C: Expanding the focus from antioxidant to endogenous neuromodulator

SJ Ballaz, GV Rebec - Pharmacological research, 2019 - Elsevier
Ascorbic acid (AA) is a water-soluble vitamin (C) found in all bodily organs. Most mammals
synthesize it, humans are required to eat it, but all mammals need it for healthy functioning …

Assessment of neurotoxicity following single and co-exposure of cadmium and mercury in adult zebrafish: behavior alterations, oxidative stress, gene expression, and …

UN Patel, UD Patel, AV Khadayata, RK Vaja… - Water, Air, & Soil …, 2021 - Springer
In this study, alterations in behavior, oxidative stress, and related gene expressions, as well
as histopathological changes in the brain, of zebrafish were evaluated following exposure to …

Potential of zebrafish as a model for exploring the role of the amygdala in emotional memory and motivational behavior

S Perathoner, ML Cordero‐Maldonado… - Journal of …, 2016 - Wiley Online Library
Emotion is a key aspect of behavior, enabling humans and animals to assign either positive
or negative values to sensory inputs and thereby to make appropriate decisions. Classical …

Anxiolytic effects of ascorbic acid and ketamine in mice

DB Fraga, G Olescowicz, M Moretti, A Siteneski… - Journal of Psychiatric …, 2018 - Elsevier
Some studies have demonstrated that ascorbic acid, similarly to ketamine, exhibits
antidepressant-like effects mediated, at least in part, by modulation of the glutamatergic …

[HTML][HTML] Gallic and ascorbic acids supplementation alleviate cognitive deficits and neuropathological damage exerted by cadmium chloride in Wistar rats

O Adebiyi, K Adigun, P David-Odewumi, U Akindele… - Scientific reports, 2022 - nature.com
Cadmium is a highly neurotoxic heavy metal that interferes with DNA repair mechanisms via
generation of reactive oxygen species. The potentials of polyphenols and antioxidants as …