Photodynamic therapy in colorectal cancer treatment—the state of the art in preclinical research

A Kawczyk-Krupka, AM Bugaj, W Latos… - Photodiagnosis and …, 2016 - Elsevier
Background Photodynamic therapy (PDT) is used in many different oncologic fields. Also in
gastroenterology, where have been a few attempts to treat both the premalignant lesion and …

Folic acid-conjugated chitosan nanoparticles enhanced protoporphyrin IX accumulation in colorectal cancer cells

SJ Yang, FH Lin, KC Tsai, MF Wei, HM Tsai… - Bioconjugate …, 2010 - ACS Publications
Folic acid can be covalently conjugated to chitosan molecules via its γ-carboxyl moiety and
thus retain a high affinity for colorectal cancer cells bearing folate receptor overexpression …

The practicalities of photodynamic therapy in acne vulgaris

MN Taylor, ML Gonzalez - British Journal of Dermatology, 2009 - academic.oup.com
A staple clinical skill in a dermatologist's repertoire is the ability to treat acne vulgaris
effectively. Light‐based therapies such as photodynamic therapy (PDT) widen the …

Alginate-folic acid-modified chitosan nanoparticles for photodynamic detection of intestinal neoplasms

SJ Yang, FH Lin, HM Tsai, CF Lin, HC Chin, JM Wong… - Biomaterials, 2011 - Elsevier
Colorectal cancer is one of the leading causes of cancer death and often goes undetected
with current colonoscopy practices. Improved methods of detecting dysplasia and tumors …

Colorectal cancer cell detection by 5-aminolaevulinic acid-loaded chitosan nano-particles

SJ Yang, MJ Shieh, FH Lin, PJ Lou, CL Peng, MF Wei… - Cancer Letters, 2009 - Elsevier
Colorectal cancer is one of the leading causes of malignant death in Taiwan because it often
remains undetected until later stages of the disease. In this study, we designed an oral form …

Photodynamic detection of oral cancers with high-performance chitosan-based nanoparticles

SJ Yang, CF Lin, ML Kuo, CT Tan - Biomacromolecules, 2013 - ACS Publications
Oral cancer, a subtype of head and neck cancer, is one of the leading causes of cancer
death and is difficult to detect in the early stages. Improved methods of detecting primary oral …

Primary Photodamage Sites and Mitochondrial Events after Foscan® Photosensitization of MCF‐7 Human Breast Cancer Cells

MH Teiten, S Marchal, MA D'Hallewin… - Photochemistry and …, 2003 - Wiley Online Library
To determine the initial photodamage sites of Foscan®‐mediated photodynamic treatment,
we evaluated the enzymatic activities in selected organelles immediately after light exposure …

5‐Aminolevulinic Acid–based Photochemical Internalization of the Immunotoxin MOC31‐gelonin Generates Synergistic Cytotoxic Effects In Vitro

PK Selbo, O Kaalhus, G Sivam… - Photochemistry and …, 2001 - Wiley Online Library
Photochemical internalization (PCI) is a novel method for the endosomal or lysosomal
release of membrane‐impermeable molecules into the cytosol of target cells. This novel …

Photodynamic therapy and the alimentary tract

CR Selvasekar, N Birbeck, T McMillan… - Alimentary …, 2001 - Wiley Online Library
Photodynamic therapy offers the possibility of relatively selective tumour necrosis and
normal tissue healing. It has many potential applications but as yet no clear role. Articles …

[HTML][HTML] Enhancement of 5-aminolevulinic acid phototoxicity by encapsulation in polysaccharides based nanocomplexes for photodynamic therapy application

A Di Martino, A Pavelkova, PS Postnikov… - … of Photochemistry and …, 2017 - Elsevier
Polysaccharides based nanocomplexes have been developed for encapsulation, controlled
delivery and to enhance the phototoxicity of the photosensitizer 5-aminolevulinic acid for …