In recent years a substantial number of findings have been made in the area of
immunometabolism, by which we mean the changes in intracellular metabolic pathways in …

Macrophages play a major role in the immune system, both as antimicrobial effector cells
and as immunoregulatory cells, which induce, suppress or modulate adaptive immune …

Macrophages are cells of the innate immunity constituting the mononuclear phagocyte
system and endowed with remarkable different roles essential for defense mechanisms …

Traditionally cellular respiration or metabolism has been viewed as catabolic and anabolic
pathways generating energy and biosynthetic precursors required for growth and general …

Macrophages are cells of innate immunity and are derived from circulating monocytes and
embryonic yolk sac. They exhibit high plasticity and polarize functionally in response to …

Leishmaniasis remains a public health concern around the world that primarily affects poor
folks of the developing world spanning across 98 countries with mortality of 0.2 million to 0.4 …

Macrophages are heterogeneous and plastic, and play several diverse functions in immune
responses. Emerging data provide evidence of multiple roles for metabolic pathways in the …

Malnutrition is commonly associated with increased infectious disease susceptibility and
severity. Whereas malnutrition might enhance the incidence of disease as well as its …

Epigallocatechin-3-gallate (EGCG), a dietary polyphenol (flavanol) from green tea,
possesses leishmanicidal and antitrypanosomal activity. Mitochondrial damage was …

Preterm newborns are highly susceptible to bacterial infections. This susceptibility is
regarded as being due to immaturity of multiple pathways of the immune system. However, it …