Abstract The World Health Organization Classification of Lymphoid Neoplasms identifies
Burkitt lymphoma/leukemia as a highly aggressive mature B-cell neoplasm consisting of …

The origin of human lymphomas has been studied by various approaches, including
histology and immunophenotyping. In some types of lymphoma these studies suggested the …

High-throughput single-cell RNA sequencing is a powerful technique but only generates
short reads from one end of a cDNA template, limiting the reconstruction of highly diverse …

Epstein–Barr virus (EBV) is an extremely successful virus, infecting more than 90% of the
human population worldwide. After primary infection, the virus persists for the life of the host …

The diagnostic category of Burkitt's lymphoma encompasses a closely related group of
aggressive B-cell tumors that includes sporadic, endemic, and human immunodeficiency …

In the immune system, many tolerance checkpoints exist to prevent self-antigens from
stimulating the relentless growth of self-reactive B and T lymphocytes. The genes and …

Burkitt lymphoma (BL) is an aggressive B-cell malignancy with endemic, sporadic and
immunodeficiency-associated variants. It has been known for many years that the …

Several cell types have been suggested as giving rise to chronic lymphocytic leukemia
(CLL), and these suggestions have reflected the sophistication of technology available at the …

The Epstein–Barr virus (EBV) nuclear antigen (EBNA)-1 is the only viral protein expressed in
all EBV-carrying malignancies, but its contribution to oncogenesis has remained enigmatic …

In the human, most IgM+ IgD+ as well as CD5* peripheral blood B cells express unmutated
V genes and thus can be assigned to a pre‐germinal centre (GC) stage of development. The …