Adult Burkitt leukemia and lymphoma
KA Blum, G Lozanski, JC Byrd - Blood, 2004 - ashpublications.org
Abstract The World Health Organization Classification of Lymphoid Neoplasms identifies
Burkitt lymphoma/leukemia as a highly aggressive mature B-cell neoplasm consisting of …
Burkitt lymphoma/leukemia as a highly aggressive mature B-cell neoplasm consisting of …
Cellular origin of human B-cell lymphomas
The origin of human lymphomas has been studied by various approaches, including
histology and immunophenotyping. In some types of lymphoma these studies suggested the …
histology and immunophenotyping. In some types of lymphoma these studies suggested the …
[HTML][HTML] High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes
High-throughput single-cell RNA sequencing is a powerful technique but only generates
short reads from one end of a cDNA template, limiting the reconstruction of highly diverse …
short reads from one end of a cDNA template, limiting the reconstruction of highly diverse …
B cells under influence: transformation of B cells by Epstein–Barr virus
R Küppers - Nature Reviews Immunology, 2003 - nature.com
Epstein–Barr virus (EBV) is an extremely successful virus, infecting more than 90% of the
human population worldwide. After primary infection, the virus persists for the life of the host …
human population worldwide. After primary infection, the virus persists for the life of the host …
Molecular biology of Burkitt's lymphoma
The diagnostic category of Burkitt's lymphoma encompasses a closely related group of
aggressive B-cell tumors that includes sporadic, endemic, and human immunodeficiency …
aggressive B-cell tumors that includes sporadic, endemic, and human immunodeficiency …
[HTML][HTML] Multistep pathogenesis of autoimmune disease
CC Goodnow - Cell, 2007 - cell.com
In the immune system, many tolerance checkpoints exist to prevent self-antigens from
stimulating the relentless growth of self-reactive B and T lymphocytes. The genes and …
stimulating the relentless growth of self-reactive B and T lymphocytes. The genes and …
Epstein–Barr virus and Burkitt lymphoma
G Brady, GJ MacArthur, PJ Farrell - Postgraduate medical …, 2008 - academic.oup.com
Burkitt lymphoma (BL) is an aggressive B-cell malignancy with endemic, sporadic and
immunodeficiency-associated variants. It has been known for many years that the …
immunodeficiency-associated variants. It has been known for many years that the …
Cellular origin (s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities
N Chiorazzi, M Ferrarini - Blood, The Journal of the American …, 2011 - ashpublications.org
Several cell types have been suggested as giving rise to chronic lymphocytic leukemia
(CLL), and these suggestions have reflected the sophistication of technology available at the …
(CLL), and these suggestions have reflected the sophistication of technology available at the …
The Epstein–Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species
B Gruhne, R Sompallae, D Marescotti… - Proceedings of the …, 2009 - National Acad Sciences
The Epstein–Barr virus (EBV) nuclear antigen (EBNA)-1 is the only viral protein expressed in
all EBV-carrying malignancies, but its contribution to oncogenesis has remained enigmatic …
all EBV-carrying malignancies, but its contribution to oncogenesis has remained enigmatic …
Somatic hypermutation in normal and transformed human B cells
U Klien, T Goasens, M Fischer, H Kanzler… - Immunological …, 1998 - Wiley Online Library
In the human, most IgM+ IgD+ as well as CD5* peripheral blood B cells express unmutated
V genes and thus can be assigned to a pre‐germinal centre (GC) stage of development. The …
V genes and thus can be assigned to a pre‐germinal centre (GC) stage of development. The …