Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency
D Gaudet, J de Wal, K Tremblay, S Déry… - Atherosclerosis …, 2010 - Elsevier
Alipogene tiparvovec (AAV1-LPLS447X) gene therapy is developed to prevent
complications and decrease the clinical morbidity of lipoprotein lipase deficiency (LPLD) …
complications and decrease the clinical morbidity of lipoprotein lipase deficiency (LPLD) …
Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgery
R Hall - Journal of Cardiothoracic and Vascular Anesthesia, 2013 - jcvaonline.com
THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …
Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review
Cancer cachexia is a polygenic and complex syndrome. Genetic variations in regulation of
the inflammatory response, muscle and fat metabolic pathways, and pathways in appetite …
the inflammatory response, muscle and fat metabolic pathways, and pathways in appetite …
Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies
Cancer cachexia is a complex and multifactorial disease. Evolving definitions highlight the
fact that a diverse range of biological processes contribute to cancer cachexia. Part of the …
fact that a diverse range of biological processes contribute to cancer cachexia. Part of the …
Effects of minimal extracorporeal circulation on the systemic inflammatory response and the need for transfusion after coronary bypass grafting surgery
ME Elçi, A Kahraman, E Mutlu… - Cardiology research and …, 2019 - Wiley Online Library
Objectives. The aim of this study is to compare the effects of the minimal extracorporeal
circulation (MiECT) on postoperative systemic inflammatory response and the need for …
circulation (MiECT) on postoperative systemic inflammatory response and the need for …
Associations between LPL gene polymorphisms and coronary artery disease: evidence based on an updated and cumulative meta-analysis
WQ Ma, Y Wang, XQ Han, Y Zhu, NF Liu - Bioscience reports, 2018 - portlandpress.com
Lipoprotein lipase (LPL) is widely linked to lipid and lipoprotein metabolism, but its effects on
coronary artery disease (CAD) are not clearly elucidated. The aim of the present study was …
coronary artery disease (CAD) are not clearly elucidated. The aim of the present study was …
Comparison of new technology integrated and nonintegrated arterial filters used in cardiopulmonary bypass surgery: a randomized, prospective, and single blind …
Ö Gürsu, S Isbir, K Ak, F Gerin… - BioMed Research …, 2013 - Wiley Online Library
Background. Innovative cardiopulmonary bypass (CPB) settings have been developed in
order to integrate the concepts of “surface‐coating,”“blood‐filtration,” and “miniaturization.” …
order to integrate the concepts of “surface‐coating,”“blood‐filtration,” and “miniaturization.” …
Postoperative statin therapy attenuates the intensity of systemic inflammation and increases fibrinolysis after coronary artery bypass grafting
A total of 25 patients undergoing coronary artery bypass grafting (CABG) were included in
the study. Patients received statin (20 mg daily) postoperatively for 2 weeks. All analyses …
the study. Patients received statin (20 mg daily) postoperatively for 2 weeks. All analyses …
Associations of lipoprotein lipase S447X and apolipoprotein E genotypes with low-density lipoprotein subfractions in Turkish patients with coronary artery disease
Background: This study investigated associations of specific lipoprotein lipase (LPL) S447X
and apolipoprotein (Apo) E allelic patterns with low-density lipoprotein (LDL) size and …
and apolipoprotein (Apo) E allelic patterns with low-density lipoprotein (LDL) size and …
Hypertriglyceridaemia, LPL deficiency and pancreatitis-pathogenesis and therapeutic options
SP Munigoti, A Rees - The British Journal of Diabetes & …, 2011 - journals.sagepub.com
Severe hypertriglyceridaemia (HTG) is recognised as the third most common cause of acute
pancreatitis. While secondary causes of HTG such as excess alcohol, obesity and diabetes …
pancreatitis. While secondary causes of HTG such as excess alcohol, obesity and diabetes …