A brief introduction to chemical reaction optimization
From the start of a synthetic chemist's training, experiments are conducted based on recipes
from textbooks and manuscripts that achieve clean reaction outcomes, allowing the scientist …
from textbooks and manuscripts that achieve clean reaction outcomes, allowing the scientist …
Self-driving laboratories for chemistry and materials science
Self-driving laboratories (SDLs) promise an accelerated application of the scientific method.
Through the automation of experimental workflows, along with autonomous experimental …
Through the automation of experimental workflows, along with autonomous experimental …
Technological innovations in photochemistry for organic synthesis: flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry
L Buglioni, F Raymenants, A Slattery… - Chemical …, 2021 - ACS Publications
Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …
of attention, providing a plethora of opportunities to synthetic organic chemists. However …
Carboxylic acids as adaptive functional groups in metallaphotoredox catalysis
Conspectus The development of palladium-catalyzed cross-coupling methods for the
activation of C (sp2)–Br bonds facilitated access to arene-rich molecules, enabling a …
activation of C (sp2)–Br bonds facilitated access to arene-rich molecules, enabling a …
Photocatalysis in the life science industry
L Candish, KD Collins, GC Cook, JJ Douglas… - Chemical …, 2021 - ACS Publications
In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science
industry require access to mild and robust synthetic methodologies to systematically modify …
industry require access to mild and robust synthetic methodologies to systematically modify …
Bayesian reaction optimization as a tool for chemical synthesis
Reaction optimization is fundamental to synthetic chemistry, from optimizing the yield of
industrial processes to selecting conditions for the preparation of medicinal candidates …
industrial processes to selecting conditions for the preparation of medicinal candidates …
Organic thermally activated delayed fluorescence (TADF) compounds used in photocatalysis
MA Bryden, E Zysman-Colman - Chemical Society Reviews, 2021 - pubs.rsc.org
Organic compounds that show Thermally Activated Delayed Fluorescence (TADF) have
become wildly popular as next-generation emitters in organic light emitting diodes (OLEDs) …
become wildly popular as next-generation emitters in organic light emitting diodes (OLEDs) …
Automated self-optimization, intensification, and scale-up of photocatalysis in flow
The optimization, intensification, and scale-up of photochemical processes constitute a
particular challenge in a manufacturing environment geared primarily toward thermal …
particular challenge in a manufacturing environment geared primarily toward thermal …
Alkyl carbon–carbon bond formation by Nickel/Photoredox cross‐coupling
JA Milligan, JP Phelan, SO Badir… - Angewandte Chemie …, 2019 - Wiley Online Library
The union of photoredox and nickel catalysis has resulted in a renaissance in radical
chemistry as well as in the use of nickel‐catalyzed transformations, specifically for carbon …
chemistry as well as in the use of nickel‐catalyzed transformations, specifically for carbon …
Data-science driven autonomous process optimization
M Christensen, LPE Yunker, F Adedeji… - Communications …, 2021 - nature.com
Autonomous process optimization involves the human intervention-free exploration of a
range process parameters to improve responses such as product yield and selectivity …
range process parameters to improve responses such as product yield and selectivity …