The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Meibomian gland dysfunction (MGD) is highly prevalent and is the leading cause of
evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum …

Diagnostic tests of meibomian gland dysfunction (MGD) and of MGD-related disorders are
based on the demonstration of abnormal anatomy and physiology of the glands and the …

Human cornea is covered by an aqueous tear film, and the outermost layer of the tear film is
coated by lipids. This so-called tear film lipid layer (TFLL) reduces surface tension of the tear …

Purpose Inflammatory molecules have been demonstrated in the tear film of patients with
severe dry eye disease (DED). However, little attention has been paid to the most frequent …

Purpose.: The lipid layer of the tear film forms a barrier to evaporation. Evaporation is a
major cause of tear thinning between blinks and tear breakup. The purpose of this study was …

Meibomian gland dysfunction is one of the most common causes of dry eye resulting in
morphology changes to the meibomian glands. Meibography provides an in vivo means to …

Human meibomian gland secretions (MGS, or meibum) are formed from a complex mixture
of lipids of different classes such as wax esters, cholesteryl esters,(O-acyl)-ω-hydroxy fatty …

Dry eye is a common yet complex condition. Intrinsic and extrinsic factors can cause
dysfunction of the lids, lacrimal glands, meibomian glands, ocular surface cells, or neural …

This review discusses the current understanding of tear-film physiology and mathematical
models for some of its dynamics. First, a brief introduction to the tear film and the ocular …