[HTML][HTML] Investigating mitochondrial redox state using NADH and NADPH autofluorescence
TS Blacker, MR Duchen - Free Radical Biology and Medicine, 2016 - Elsevier
The redox states of the NAD and NADP pyridine nucleotide pools play critical roles in
defining the activity of energy producing pathways, in driving oxidative stress and in …
defining the activity of energy producing pathways, in driving oxidative stress and in …
Advanced applications of RNA sequencing and challenges
Next-generation sequencing technologies have revolutionarily advanced sequence-based
research with the advantages of high-throughput, high-sensitivity, and high-speed. RNA-seq …
research with the advantages of high-throughput, high-sensitivity, and high-speed. RNA-seq …
Integrating knowledge and omics to decipher mechanisms via large‐scale models of signaling networks
Signal transduction governs cellular behavior, and its dysregulation often leads to human
disease. To understand this process, we can use network models based on prior …
disease. To understand this process, we can use network models based on prior …
Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects
FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …
provides a comprehensive and up-to-date account on the latest developments in the area of …
[HTML][HTML] High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes
Understanding the aspects of the cell functionality that account for disease or drug action
mechanisms is a main challenge for precision medicine. Here we propose a new method …
mechanisms is a main challenge for precision medicine. Here we propose a new method …
The promise of multi-omics and clinical data integration to identify and target personalized healthcare approaches in autism spectrum disorders
R Higdon, RK Earl, L Stanberry, CM Hudac… - Omics: a journal of …, 2015 - liebertpub.com
Complex diseases are caused by a combination of genetic and environmental factors,
creating a difficult challenge for diagnosis and defining subtypes. This review article …
creating a difficult challenge for diagnosis and defining subtypes. This review article …
Transcriptome and cell physiological analyses in different rice cultivars provide new insights into adaptive and salinity stress responses
E Formentin, C Sudiro, G Perin, S Riccadonna… - Frontiers in plant …, 2018 - frontiersin.org
Salinity tolerance has been extensively investigated in recent years due to its agricultural
importance. Several features, such as the regulation of ionic transporters and metabolic …
importance. Several features, such as the regulation of ionic transporters and metabolic …
A comparison of mechanistic signaling pathway activity analysis methods
Understanding the aspects of cell functionality that account for disease mechanisms or drug
modes of action is a main challenge for precision medicine. Classical gene-based …
modes of action is a main challenge for precision medicine. Classical gene-based …
[HTML][HTML] A gene pathway enrichment method based on improved TF-IDF algorithm
S Xu, Y Leng, G Feng, C Zhang, M Chen - Biochemistry and Biophysics …, 2023 - Elsevier
Gene pathway enrichment analysis is a widely used method to analyze whether a gene set
is statistically enriched on certain biological pathway network. Current gene pathway …
is statistically enriched on certain biological pathway network. Current gene pathway …
Understanding disease mechanisms with models of signaling pathway activities
Background Understanding the aspects of the cell functionality that account for disease or
drug action mechanisms is one of the main challenges in the analysis of genomic data and …
drug action mechanisms is one of the main challenges in the analysis of genomic data and …