Gene drives are selfish genetic elements that are transmitted to progeny at super-Mendelian
(> 50%) frequencies. Recently developed CRISPR–Cas9-based gene-drive systems are …

Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …

Mosquitoes bring global health problems by transmitting parasites and viruses such as
malaria and dengue. Unfortunately, current insecticide-based control strategies are only …

Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …

Gene drives are engineered alleles that can bias inheritance in their favor, allowing them to
spread throughout a population. They could potentially be used to modify or suppress pest …

Viruses in built environments (BEs) raise public health concerns, yet they are generally less
studied than bacteria. To better understand viral dynamics in BEs, this study assesses …

Genetic modification for the control of mosquitoes is frequently touted as a solution for a
variety of vector-borne diseases. There has been some success using non-insecticidal …

Gene drive elements promote the spread of linked traits and can be used to change the
composition or fate of wild populations. Cleave and Rescue (ClvR) drive elements sit at a …

Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-
associated proteins) systems provide bacteria and archaea with an adaptive immune …

CRISPR-based gene drives have the potential to spread within populations and are
considered as promising vector control tools. A doublesex-targeting gene drive was able to …