Sexual differentiation of malaria parasites from the asexual blood stage into gametocytes is
an essential part of the life cycle, as gametocytes are the form that is taken up by the …

Apicomplexan parasites are protozoan organisms that are characterised by complex life
cycles and they include medically important species, such as the malaria parasite …

Gametocytogenesis, the process by which malaria parasites produce sexual forms that can
infect mosquitoes, is essential for the transmission of malaria. A transcriptional switch of the …

Over the past decade, we have witnessed significant progresses in understanding gene
regulation in Apicomplexa including the human malaria parasite, Plasmodium falciparum …

Mutually exclusive expression of the var multigene family is key to immune evasion and
pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct …

Plasmodium parasites are reliant on the Apicomplexan AP2 (ApiAP2) transcription factor
family to regulate gene expression programs. AP2 DNA binding domains have no homologs …

Plasmodium falciparum, the human malaria parasite, infects two hosts and various cell
types, inducing distinct morphological and physiological changes in the parasite in response …

Human malaria is a devastating disease and a major cause of poverty in resource-limited
countries. To develop and adapt within hosts Plasmodium falciparum undergoes drastic …

Heterochromatin-associated gene silencing controls multiple physiological processes in
malaria parasites, however, little is known concerning the regulatory network and cis-acting …

The malaria parasite has a complex life cycle exhibiting phenotypic and morphogenic
variations in two different hosts by existing in heterogeneous developmental states. To …