Tumor microenvironment-derived exosomes: A double-edged sword for advanced T cell-based immunotherapy

Y Lu, J Zheng, P Lin, Y Lin, Y Zheng, Z Mai, X Chen… - ACS …, 2024 - ACS Publications
The tumor microenvironment (TME) plays a crucial role in cancer progression and immune
evasion, partially mediated by the activity of the TME-derived exosomes. These extracellular …

Extracellular Vesicles and Immune System Function: Exploring Novel Approaches to Colorectal Cancer Immunotherapy

A Biondi, M Vacante, R Catania, G Sangiorgio - Biomedicines, 2024 - pmc.ncbi.nlm.nih.gov
This review explores the emerging role of extracellular vesicles (EVs) in modulating immune
system function and their application in novel cancer immunotherapy strategies, with a focus …

[HTML][HTML] Innate Immune Cells in Melanoma: Implications for Immunotherapy

M Trocchia, A Ventrici, L Modestino… - International Journal of …, 2024 - mdpi.com
The innate immune system, composed of neutrophils, basophils, eosinophils, myeloid-
derived suppressor cells (MDSCs), macrophages, dendritic cells (DCs), mast cells (MCs) …

NK cell based immunotherapy against oral squamous cell carcinoma

Y Zhang, J Xie, H Wu, J Huang, D Zheng… - Frontiers in …, 2024 - frontiersin.org
Oral squamous cell carcinoma (OSCC), a major subtype of head and neck cancers, presents
significant challenges due to its aggressive feature and limited therapeutic efficacy of …

Quercetin exerts anti-tumor immune mechanism by regulating IL-6/JAK2/STAT3 signaling pathway to deplete Treg cells

Y Liao, X Xie, C Zhang, H Zhong, L Shan, P Yu, L Xu - Toxicon, 2024 - Elsevier
Breast cancer is still the leading cause of death among women worldwide. Due to the lack of
effective drug targets, triple-negative breast cancer has a worse prognosis and higher …

[HTML][HTML] Immunotherapy in the Battle Against Bone Metastases: Mechanisms and Emerging Treatments

FN Hamza, KS Mohammad - Pharmaceuticals, 2024 - mdpi.com
Bone metastases are a prevalent complication in advanced cancers, particularly in breast,
prostate, and lung cancers, and are associated with severe skeletal-related events (SREs) …

Immunotherapy in Oncology: A Comprehensive Overview from a Pathological Perspective

C Díaz del Arco - 2024 - Springer
Immunotherapy (IT) has emerged as a groundbreaking approach in the field of oncology,
offering new hope in the fight against cancer. However, the true power of IT lies in its precise …

Importance of specific NK cell subsets for antitumor immunity in HPV+ cancers

M O'Hara - 2024 - digitalcommons.library.tmc.edu
High-risk type human papillomaviruses (HPV) are associated with genital and oral cancers,
and the incidence of HPV+ head and neck squamous cell cancers is fast increasing …