Chronic wounds are associated with considerable patient morbidity and present a significant
economic burden to the healthcare system. Often, chronic wounds are in a state of persistent …

The human amniotic membrane (hAM) is a collagen-based extracellular matrix derived from
the human placenta. It is a readily available, inexpensive, and naturally biocompatible …

To compare the therapeutic efficacy of cryopreserved amniotic membrane (AM) grafts and
standard of care (SOC) in treating nonhealing wounds (NHW) through a prospective …

The aim of this study was to compare concentrations of endogenous N-acylethanolamine
(NAE) lipid mediators—palmitoylethanolamide (PEA), oleoylethanolamide (OEA), and …

Insufficient levels of nitric oxide may lead to chronic and acute wounds. Additionally, it is
crucial that nitric oxide is prepared in a controlled-release manner due to its gaseous nature …

Hard-to-heal wounds do not heal spontaneously and need long-term care provided by
specialists. That burdens the patients as well as the healthcare systems. Such wounds arise …

Objective: Venous leg ulcers (VLUs) are often large and complicated wounds that, despite
combinations of advanced wound care techniques and systemic treatment of underlying …

Significance: Chronic wounds can lead to poor outcomes for patients, with risks, including
amputation and death. In the United States, chronic wounds affect 2.5% of the population …

Cardiac ischemic reperfusion injury (IRI) is paradoxically instigated by reestablishing blood‐
flow to ischemic myocardium typically from a myocardial infarction (MI). Although …

Abstract Purpose of This Review Skin grafting is a surgical procedure that involves replacing
damaged or missing skin with healthy skin. This technique helps protect wounds, promotes …