Biologics Versus JAK Inhibitors. Part II: Risk of Infections. A Narrative Review

M Mansilla-Polo, D Morgado-Carrasco - Dermatology and Therapy, 2024 - Springer
Introduction The risk of infections associated with biological drugs (BD) and Janus kinase
inhibitors (JAKi) has been extensively explored in the literature. However, there is a dearth …

Exploring the complex link between obesity and intelligence: Evidence from systematic review, updated meta‐analysis, and Mendelian randomization

SY Yun, JY Yun, C Lim, H Oh, E Son, K Shin… - Obesity …, 2024 - Wiley Online Library
Obesity is a major public health concern associated with a higher risk of various
comorbidities. Some studies have explored the impact of obesity on cognitive function and …

Comparative safety of oral Janus kinase inhibitors versus dupilumab in patients with atopic dermatitis: A population-based cohort study

SYC Tsai, W Phipatanakul, EB Hawryluk… - Journal of Allergy and …, 2024 - Elsevier
Background Systemic Janus kinase inhibitors (JAKi) and dupilumab both have emerged as
promising therapeutics for atopic dermatitis (AD). Dupilumab has a favorable safety profile …

Janus kinase inhibitors in atopic dermatitis: an umbrella review of meta-analyses

Q He, X Xie, Q Chen, W Li, Z Song, X Wang… - Frontiers in …, 2024 - frontiersin.org
Background Clinicians and healthcare policymakers have been drenched with a deluge of
overlapping meta-analyses (MAs), and the necessity for comprehensive and clearly defined …

A systematic review and Meta-analysis of Mobile Health Applications and Telemonitoring in atopic Dermatitis Self-Management

I Cherrez-Ojeda, K Robles-Velasco, MF Osorio… - Dermatology and …, 2024 - Springer
Introduction Up to 25% of children and 5.6% of adults in the USA have atopic dermatitis
(AD), with substantial impacts on quality of life. Effective control can be challenging despite …

The Impact of Assisted Reproductive Technologies on ADHD: A Systematic Review and Meta-analysis

S Hwang, J Jung, H Moon, HW Kim, JP Yoon… - Asian Journal of …, 2024 - Elsevier
Background The escalating utilization of assisted reproductive technology (ART) in
response to global infertility rates has spurred research into its complications. Short-term …

[HTML][HTML] Abrocitinib: A Comprehensive Review of its Efficacy and Safety in Dermatology

S Dogra, S Shah, M Gupta, A Sharma… - Indian Dermatology …, 2024 - journals.lww.com
Abrocitinib is a novel oral small molecule which acts as a selective JAK-1 inhibitor. Currently
approved for use in moderate-to-severe cases of atopic dermatitis, this drug is gaining a …

Novel investigational drugs for alopecia areata and future perspectives

I Chim, R Ghiya, RD Sinclair… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Alopecia areata (AA) is an immune-mediated disease that causes non-scarring
hair loss. While acute, solitary patches often spontaneously remit, developing secondary …

Exploring the handedness-breast cancer nexus: a comprehensive analysis via systematic review, meta-analysis, and Mendelian randomization

CY Oh, E Kim, K Kim, H Oh, JP Yoon… - Therapeutic …, 2024 - journals.sagepub.com
Background: Given the widespread prevalence of breast cancer as a global malignancy,
there is a compelling need to delve into its risk determinants. Objective: This study aims to …

Therapeutic Potential of Targeting the JAK/STAT Pathway in Psoriasis: Focus on TYK2 Inhibition

M Dragotto, M D'Onghia, E Trovato, L Tognetti… - Journal of Clinical …, 2024 - mdpi.com
Psoriasis is an inflammatory skin disease with a chronic relapsing course and an often-
detrimental impact on patients' quality of life. Thanks to incredible advances in research over …