Guardians of the mycobacterial genome: A review on DNA repair systems in Mycobacterium tuberculosis
A Singh - Microbiology, 2017 - microbiologyresearch.org
The genomic integrity of Mycobacterium tuberculosis is continuously threatened by the
harsh survival conditions inside host macrophages, due to immune and antibiotic stresses …
harsh survival conditions inside host macrophages, due to immune and antibiotic stresses …
DNA Replication in Mycobacterium tuberculosis
Z Ditse, MH Lamers, DF Warner - Microbiology spectrum, 2017 - Am Soc Microbiol
Faithful replication and maintenance of the genome are essential to the ability of any
organism to survive and propagate. For an obligate pathogen such as Mycobacterium …
organism to survive and propagate. For an obligate pathogen such as Mycobacterium …
Mycobacterium tuberculosis thymidylate synthase (ThyX) is a target for plumbagin, a natural product with antimycobacterial activity
Plumbagin derived from the plant Plumbago indica, known as Chitrak in India, is an example
of a medicinal compound used traditionally to cure a variety of ailments. Previous reports …
of a medicinal compound used traditionally to cure a variety of ailments. Previous reports …
Roles for mycobacterial DinB2 in frameshift and substitution mutagenesis
Translesion synthesis by translesion polymerases is a conserved mechanism of DNA
damage tolerance. In bacteria, DinB enzymes are the widely distributed promutagenic …
damage tolerance. In bacteria, DinB enzymes are the widely distributed promutagenic …
Epigenetic Phosphorylation Control of Mycobacterium tuberculosis Infection and Persistence
M Richard-Greenblatt, Y Av-Gay - Microbiology spectrum, 2017 - Am Soc Microbiol
Reversible protein phosphorylation is the most common type of epigenetic posttranslational
modification in living cells used as a major regulation mechanism of biological processes …
modification in living cells used as a major regulation mechanism of biological processes …
DNA binding and gene regulatory functions of MSMEG_2295, a repressor encoded by the dinB2 operon of Mycobacterium smegmatis
MSMEG_2295 is a TetR family protein encoded by the first gene of a Mycobacterium
smegmatis (Msm) operon that expresses the gene for DinB2 (MSMEG_2294), a translesion …
smegmatis (Msm) operon that expresses the gene for DinB2 (MSMEG_2294), a translesion …
Apoptosis like symptoms associated with abortive infection of Mycobacterium smegmatis by mycobacteriophage D29
Mycobacteriophages are phages that infect mycobacteria resulting in their killing. Although
lysis is the primary mechanism by which mycobacteriophages cause cell death, others such …
lysis is the primary mechanism by which mycobacteriophages cause cell death, others such …
The effects of mycobacterial RmlA perturbation on cellular dNTP pool, cell morphology, and replication stress in Mycobacterium smegmatis
The concerted action of DNA replication and cell division has been extensively investigated
in eukaryotes. Well demarcated checkpoints have been identified in the cell cycle, which …
in eukaryotes. Well demarcated checkpoints have been identified in the cell cycle, which …
DNA Replication Fidelity in the Mycobacterium tuberculosis Complex
Mycobacterium tuberculosis is genetically isolated, with no evidence for horizontal gene
transfer or the acquisition of episomal genetic information in the modern evolution of strains …
transfer or the acquisition of episomal genetic information in the modern evolution of strains …
Evidence of positive regulation of mycobacteriophage D29 early gene expression obtained from an investigation using a temperature-sensitive mutant of the phage
S Ghosh, R Shaw, A Sarkar… - FEMS Microbiology …, 2020 - academic.oup.com
Mycobacteriophages are phages that infect and kill Mycobacteria, several of which,
Mycobacterium tuberculosis (Mtb), for example, cause the disease tuberculosis. Although …
Mycobacterium tuberculosis (Mtb), for example, cause the disease tuberculosis. Although …