[HTML][HTML] The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment
A Giménez-Palomo, S Dodd, G Anmella… - Frontiers in …, 2021 - frontiersin.org
Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …
energy production. Several studies have found a relationship between mitochondrial …
Mitochondrial oxidative phosphorylation system (OXPHOS) deficits in schizophrenia: possible interactions with cellular processes
O Bergman, D Ben-Shachar - The Canadian Journal of …, 2016 - journals.sagepub.com
Mitochondria are key players in the generation and regulation of cellular bioenergetics,
producing the majority of adenosine triphosphate molecules by the oxidative …
producing the majority of adenosine triphosphate molecules by the oxidative …
[HTML][HTML] Aralar sequesters GABA into hyperactive mitochondria, causing social behavior deficits
Social impairment is frequently associated with mitochondrial dysfunction and altered
neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it …
neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it …
Retinal layer abnormalities as biomarkers of schizophrenia
NN Samani, FA Proudlock, V Siram… - Schizophrenia …, 2018 - academic.oup.com
Objective Schizophrenia is associated with several brain deficits, as well as visual
processing deficits, but clinically useful biomarkers are elusive. We hypothesized that retinal …
processing deficits, but clinically useful biomarkers are elusive. We hypothesized that retinal …
Mitochondrial multifaceted dysfunction in schizophrenia; complex I as a possible pathological target
D Ben-Shachar - Schizophrenia research, 2017 - Elsevier
Mitochondria are key players in various essential cellular processes beyond being the main
energy supplier of the cell. Accordingly, they are involved in neuronal synaptic transmission …
energy supplier of the cell. Accordingly, they are involved in neuronal synaptic transmission …
[HTML][HTML] Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response
T Santos-Silva, D Hazar Ülgen, CFB Lopes… - Translational …, 2023 - nature.com
Adolescent individuals exhibit great variability in cortical dynamics and behavioral
outcomes. The developing adolescent brain is highly sensitive to social experiences and …
outcomes. The developing adolescent brain is highly sensitive to social experiences and …
[HTML][HTML] Genetic relationship between schizophrenia and nicotine dependence
It is well known that most schizophrenia patients smoke cigarettes. There are different
hypotheses postulating the underlying mechanisms of this comorbidity. We used summary …
hypotheses postulating the underlying mechanisms of this comorbidity. We used summary …
[HTML][HTML] The druggable schizophrenia genome: from repurposing opportunities to unexplored drug targets
SG Lago, S Bahn - NPJ genomic medicine, 2022 - nature.com
There have been no new drugs for the treatment of schizophrenia in several decades and
treatment resistance represents a major unmet clinical need. The drugs that exist are based …
treatment resistance represents a major unmet clinical need. The drugs that exist are based …
[HTML][HTML] The early growth response protein 1-miR-30a-5p-neurogenic differentiation factor 1 axis as a novel biomarker for schizophrenia diagnosis and treatment …
S Liu, F Zhang, YY Shugart, L Yang, X Li, Z Liu… - Translational …, 2017 - nature.com
To date, diagnosis of schizophrenia is still based on clinical interviews and careful
observations, which is subjective and variable, and can lead to misdiagnosis and/or delay in …
observations, which is subjective and variable, and can lead to misdiagnosis and/or delay in …
Neuroprotective Effects of Açaí (Euterpe oleracea Mart.) against Rotenone In Vitro Exposure
AK Machado, AC Andreazza… - Oxidative medicine …, 2016 - Wiley Online Library
Neuropsychiatric diseases, such as bipolar disorder (BD) and schizophrenia (SCZ), have a
very complex pathophysiology. Several current studies describe an association between …
very complex pathophysiology. Several current studies describe an association between …