Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution

P Parham, A Moffett - Nature Reviews Immunology, 2013 - nature.com
Natural killer (NK) cells have roles in immunity and reproduction that are controlled by
variable receptors that recognize MHC class I molecules. The variable NK cell receptors …

Control of human viral infections by natural killer cells

S Jost, M Altfeld - Annual review of immunology, 2013 - annualreviews.org
Natural killer (NK) cells are effector cells of the innate immune system and are important in
the control of viral infections. Their relevance is reflected by the multiple mechanisms …

Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations

FF Gonzalez-Galarza, S Christmas… - Nucleic acids …, 2010 - academic.oup.com
The allele frequency net database (http://www. allelefrequencies. net) is an online repository
that contains information on the frequencies of immune genes and their corresponding …

The evolution of natural killer cell receptors

P Carrillo-Bustamante, C Keşmir, RJ de Boer - Immunogenetics, 2016 - Springer
Natural killer (NK) cells are immune cells that play a crucial role against viral infections and
tumors. To be tolerant against healthy tissue and simultaneously attack infected cells, the …

HLA DNA sequence variation among human populations: molecular signatures of demographic and selective events

S Buhler, A Sanchez-Mazas - PloS one, 2011 - journals.plos.org
Molecular differences between HLA alleles vary up to 57 nucleotides within the peptide
binding coding region of human Major Histocompatibility Complex (MHC) genes, but it is still …

HLA/KIR restraint of HIV: surviving the fittest

AA Bashirova, R Thomas… - Annual review of …, 2011 - annualreviews.org
Multiple epidemiological studies have demonstrated associations between the human
leukocyte antigen (HLA) loci and human immunodeficiency virus (HIV) disease, and more …

Immunogenetics as a tool in anthropological studies

A Sanchez‐Mazas, M Fernandez‐Viña… - …, 2011 - Wiley Online Library
The genes coding for the main molecules involved in the human immune system–
immunoglobulins, human leucocyte antigen (HLA) molecules and killer‐cell immunoglobulin …

Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals

C Vierra-Green, D Roe, L Hou, CK Hurley… - PloS one, 2012 - journals.plos.org
The immune responses of natural killer cells are regulated, in part, by killer cell
immunoglobulin-like receptors (KIR). The 16 closely-related genes in the KIR gene system …

The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities

JA Yoder, GW Litman - Immunogenetics, 2011 - Springer
Natural killer (NK) cells affect a form of innate immunity that recognizes and eliminates cells
that are infected with certain viruses or have undergone malignant transformation. In …

Killer-Cell immunoglobulin-like receptor diversity in an admixed South American population

M Castrillon, ND Marin, AJ Karduss-Urueta… - Cells, 2022 - mdpi.com
Natural Killer (NK) cells are innate immune cells that mediate antiviral and antitumor
responses. NK cell activation and induction of effector functions are tightly regulated by the …