Background/rationale Long‐term treatment with anticholinergic agents may increase the risk
of cognitive impairment or dementia. This systematic literature review and meta‐analysis …

Drugs with anticholinergic action are widely prescribed in the elderly population due to their
potential clinical benefits. However, these benefits are limited by adverse effects which may …

Importance Anticholinergic medicines have short-term cognitive adverse effects, but it is
uncertain whether long-term use of these drugs is associated with an increased risk of …

Importance Medications that influence the risk of dementia in the elderly can be relevant for
dementia prevention. Proton pump inhibitors (PPIs) are widely used for the treatment of …

Importance Many medications have anticholinergic effects. In general, anticholinergic-
induced cognitive impairment is considered reversible on discontinuation of anticholinergic …

Importance The use of anticholinergic (AC) medication is linked to cognitive impairment and
an increased risk of dementia. To our knowledge, this is the first study to investigate the …

Dementia is one of the greatest global challenges for public health; however, the
relationship between anticholinergic drugs and dementia remains unclear. The aim of the …

The use of medication with anticholinergic properties is widespread among older subjects.
Many drugs of common use such as antispasmodics, bronchodilators, antiarrhythmics …

Abstract Purpose Although Alzheimer disease and related dementias (ADRDs) have long
been considered nonpreventable and even an inevitable consequence of aging, recent …

Background Cumulative anticholinergic exposure (anticholinergic burden) has been linked
to a number of adverse outcomes. To conduct research in this area, an agreed approach to …