Idiopathic pulmonary fibrosis: Current and future treatment

DS Glass, D Grossfeld, HA Renna… - The clinical …, 2022 - Wiley Online Library
Objectives Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease characterized
by dry cough, fatigue, and progressive exertional dyspnea. Lung parenchyma and …

Impact of antifibrotic therapy on mortality and acute exacerbation in idiopathic pulmonary fibrosis: a systematic review and meta-analysis

T Petnak, P Lertjitbanjong, C Thongprayoon, T Moua - Chest, 2021 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung
disease associated with significant morbidity and mortality. Nintedanib and pirfenidone are …

[HTML][HTML] Antifibrotics and reduced mortality in idiopathic pulmonary fibrosis: immortal time bias

S Suissa, K Suissa - American Journal of Respiratory and Critical …, 2023 - atsjournals.org
1. Khor YH, Ng Y, Barnes H, Goh NSL, McDonald CF, Holland AE. Prognosis of idiopathic
pulmonary fibrosis without anti-fibrotic therapy: a systematic review. Eur Respir Rev 2020; …

[HTML][HTML] A systematic review of the prognostic significance of the body mass index in idiopathic pulmonary fibrosis

A Zinellu, C Carru, P Pirina, AG Fois… - Journal of Clinical …, 2023 - mdpi.com
The identification of novel prognostic biomarkers might enhance individualized
management strategies in patients with idiopathic pulmonary fibrosis (IPF). Although several …

Physical activity, exercise capacity and mortality risk in people with interstitial lung disease: A systematic review and meta-analysis

V Rocha, C Paixão, A Marques - Journal of Science and Medicine in Sport, 2022 - Elsevier
Objectives Physical activity and exercise measures show potential to predict mortality in
people with interstitial lung disease. This study summarized evidence on the association …

[HTML][HTML] Real-world clinical outcomes based on body Mass Index and annualized weight change in patients with idiopathic pulmonary fibrosis

JS Lee, A Martin-Schwarze, E Freiheit, B Trzaskoma… - Advances in …, 2023 - Springer
Introduction Identification of clinical characteristics associated with prognosis for idiopathic
pulmonary fibrosis (IPF) may help to guide management decisions. This analysis utilized …

[HTML][HTML] Acute exacerbation in interstitial lung disease

EH Alhamad, JG Cal, NN Alrajhi… - Annals of Thoracic …, 2021 - journals.lww.com
BACKGROUND: Information regarding acute exacerbation (AE) in patients with interstitial
lung disease (ILD) is limited. OBJECTIVES: The objective of the study was to elucidate the …

[HTML][HTML] The influence of immortal time bias in observational studies examining associations of antifibrotic therapy with survival in idiopathic pulmonary fibrosis: A …

Q Zheng, P Otahal, IA Cox, B de Graaff… - Frontiers in …, 2023 - frontiersin.org
Background Immortal time bias (ITB) has been overlooked in idiopathic pulmonary fibrosis
(IPF). We aimed to identify the presence of ITB in observational studies examining …

[HTML][HTML] Investigation of clinical predictors of survival in idiopathic pulmonary fibrosis patients: a cohort study in Taiwan

CM Tseng, MY Chen, CY Kao… - Journal of the Chinese …, 2022 - journals.lww.com
Background: Two antifibrotic medications, pirfenidone and nintedanib, have been approved
as treatments for idiopathic pulmonary fibrosis (IPF)—a life-threatening interstitial lung …

Body mass index and weight loss as risk factors for poor outcomes in patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis

X He, J Ji, C Liu, Z Luo, J Tang, H Yan, L Guo - Annals of Medicine, 2024 - Taylor & Francis
Objective The association between nutritional status and prognosis of idiopathic pulmonary
fibrosis (IPF) remains unclear. This systematic review and meta-analysis aimed to explore …