Nanomechanical mapping of soft materials with the atomic force microscope: methods, theory and applications
R Garcia - Chemical Society Reviews, 2020 - pubs.rsc.org
Fast, high-resolution, non-destructive and quantitative characterization methods are needed
to develop materials with tailored properties at the nanoscale or to understand the …
to develop materials with tailored properties at the nanoscale or to understand the …
Imaging modes of atomic force microscopy for application in molecular and cell biology
Atomic force microscopy (AFM) is a powerful, multifunctional imaging platform that allows
biological samples, from single molecules to living cells, to be visualized and manipulated …
biological samples, from single molecules to living cells, to be visualized and manipulated …
[HTML][HTML] Force triggers YAP nuclear entry by regulating transport across nuclear pores
YAP is a mechanosensitive transcriptional activator with a critical role in cancer,
regeneration, and organ size control. Here, we show that force applied to the nucleus …
regeneration, and organ size control. Here, we show that force applied to the nucleus …
Synthesis, assembly, and applications of hybrid nanostructures for biosensing
The robust, sensitive, and selective detection of targeted biomolecules in their native
environment by prospective nanostructures holds much promise for real-time, accurate, and …
environment by prospective nanostructures holds much promise for real-time, accurate, and …
The nuclear pore complex as a flexible and dynamic gate
KE Knockenhauer, TU Schwartz - Cell, 2016 - cell.com
Nuclear pore complexes (NPCs) perforate the nuclear envelope and serve as the primary
transport gates for molecular exchange between nucleus and cytoplasm. Stripping the …
transport gates for molecular exchange between nucleus and cytoplasm. Stripping the …
Transport selectivity of nuclear pores, phase separation, and membraneless organelles
HB Schmidt, D Görlich - Trends in biochemical sciences, 2016 - cell.com
Nuclear pore complexes (NPCs) provide a selective passageway for receptor-mediated
active transport between nucleus and cytoplasm, while maintaining the distinct molecular …
active transport between nucleus and cytoplasm, while maintaining the distinct molecular …
Lost in transportation: nucleocytoplasmic transport defects in ALS and other neurodegenerative diseases
HJ Kim, JP Taylor - Neuron, 2017 - cell.com
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease
characterized by degeneration of upper and lower motor neurons in the brain and spinal …
characterized by degeneration of upper and lower motor neurons in the brain and spinal …
One ring to rule them all? Structural and functional diversity in the nuclear pore complex
J Fernandez-Martinez, MP Rout - Trends in biochemical sciences, 2021 - cell.com
The nuclear pore complex (NPC) is the massive protein assembly that regulates the
transport of macromolecules between the nucleus and the cytoplasm. Recent breakthroughs …
transport of macromolecules between the nucleus and the cytoplasm. Recent breakthroughs …
Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy
Y Sakiyama, A Mazur, LE Kapinos, RYH Lim - Nature nanotechnology, 2016 - nature.com
Nuclear pore complexes (NPCs) are biological nanomachines that mediate the bidirectional
traffic of macromolecules between the cytoplasm and nucleus in eukaryotic cells. This …
traffic of macromolecules between the cytoplasm and nucleus in eukaryotic cells. This …
HEAT repeats–versatile arrays of amphiphilic helices working in crowded environments?
SH Yoshimura, T Hirano - Journal of cell science, 2016 - journals.biologists.com
Cellular proteins do not work in isolation. Instead, they often function as part of large
macromolecular complexes, which are transported and concentrated into specific cellular …
macromolecular complexes, which are transported and concentrated into specific cellular …