Mitochondria, spermatogenesis, and male infertility–an update

S Vertika, KK Singh, S Rajender - Mitochondrion, 2020 - Elsevier
The incorporation of mitochondria in the eukaryotic cell is one of the most enigmatic events
in the course of evolution. This important organelle was thought to be only the powerhouse …

[PDF][PDF] Exploring the potential and limitations of PCR-RFLP and PCR-SSCP for SNP detection: A review

HO Hashim, MBS Al-Shuhaib - Journal of applied biotechnology …, 2019 - academia.edu
Polymerase chain reaction–single-strand conformation polymorphism (PCR-SSCP) and
PCR–restriction fragment length polymorphism (PCR-RFLP) are two independent methods …

Effect of metabolic and antioxidant supplementation on sperm parameters in oligo‐astheno‐teratozoospermia, with and without varicocele: A double‐blind placebo …

GM Busetto, A Agarwal, A Virmani, G Antonini… - Andrologia, 2018 - Wiley Online Library
Since sperm require high energy levels to perform their specialised function, it is vital that
essential nutrients are available for spermatozoa when they develop, capacitate and acquire …

Mitochondrial transplantation as a potential and novel master key for treatment of various incurable diseases

AM Roushandeh, Y Kuwahara, MH Roudkenar - Cytotechnology, 2019 - Springer
Mitochondria are attractive cellular organelles which are so interesting in both basic and
clinical research, especially after it was found that they were arisen as a bacterial intruder in …

Varicocoele‐associated male infertility: Cellular and molecular perspectives of pathophysiology

D Arya, N Balasinor, D Singh - Andrology, 2022 - Wiley Online Library
Background Varicocoele is a common risk factor associated with reduced male fertility
potential. The current understanding of varicocoele pathophysiology does not completely …

Comparative efficiency of differential diagnostic methods for the identification of BRAF V600E gene mutation in papillary thyroid cancer

Q Liu, X Jiang, W Tu, L Liu… - Experimental and …, 2024 - spandidos-publications.com
V‑Raf murine sarcoma viral oncogene homolog B1 (BRAF) encodes a serine‑threonine
kinase. The V600E point mutation in the BRAF gene is the most common mutation …

Sensitivity and applications of the PCR Single-Strand Conformation Polymorphism method

KV Kakavas - Molecular Biology Reports, 2021 - Springer
Abstract PCR Single-Strand Conformation Polymorphism is a method used to identify and
detect mutations and is now well known for its many applications on living beings. This …

Relationship between nuclear DNA fragmentation, mitochondrial DNA damage and standard sperm parameters in spermatozoa of infertile patients with …

R Derbel, H Sellami, R Sakka, AB Slima… - Journal of Gynecology …, 2021 - Elsevier
The association of leukocytospermia with male fertility is still under debate. Our objective
was to evaluate the association of leukocytospermia with sperm parameters, mitochondrial …

Associations of sperm mtDNA copy number, DNA fragmentation index, and reactive oxygen species with clinical outcomes in ART treatments

WH Shi, MJ Ye, NX Qin, ZY Zhou, XY Zhou… - Frontiers in …, 2022 - frontiersin.org
Recent studies have suggested that sperm mitochondrial DNA copy number (mtDNA-CN),
DNA fragmentation index (DFI), and reactive oxygen species (ROS) content are crucial to …

Body mass index and age correlate with antioxidant supplementation effects on sperm quality: post hoc analyses from a double‐blind placebo‐controlled trial

GM Busetto, F Del Giudice, A Virmani, A Sciarra… - Andrologia, 2020 - Wiley Online Library
Spermatozoa are vulnerable to lack of energy and oxidative stress as a result of elevated
levels of reactive oxygen species. Therefore, it is essential that appropriate nutrients are …