Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

Abstract Cyclooxygenase2 (COX2) is frequently expressed in many types of cancers
exerting a pleiotropic and multifaceted role in genesis or promotion of carcinogenesis and …

Background Neuronal pyroptosis and neuroinflammation with excess microglial activation
are widely involved in the early pathological process of ischemic stroke. Repetitive …

Traumatic brain injury (TBI) causes brain damage, which involves primary and secondary
injury mechanisms. Primary injury causes local brain damage, while secondary damage …

Traumatic brain injury (TBI) is a heterogeneous disorder that involves brain damage due to
external forces. TBI is the main factor of death and morbidity in young males with a high …

Background Neuroinflammationinduced secondary injury is an important cause of
sustained progression of spinal cord injury. Inflammatory programmed cell death pyroptosis …

Traumatic brain injury (TBI) is a leading global cause of death and disability. Here we
demonstrate in an experimental mouse model of TBI that mild forms of brain trauma cause …

Pyroptosis is a form of necrotic and inflammatory programmed cell death, which could be
characterized by cell swelling, pore formation on plasma membranes, and release of …

Background Currently, spinal cord injury (SCI) is a pathological incident that triggers several
neuropathological conditions, leading to the initiation of neuronal damage with several pro …

Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …