[HTML][HTML] Blood-based epigenome-wide analyses of 19 common disease states: A longitudinal, population-based linked cohort study of 18,413 Scottish individuals
RF Hillary, DL McCartney, HM Smith, E Bernabeu… - PLoS …, 2023 - journals.plos.org
Background DNA methylation is a dynamic epigenetic mechanism that occurs at cytosine-
phosphate-guanine dinucleotide (CpG) sites. Epigenome-wide association studies (EWAS) …
phosphate-guanine dinucleotide (CpG) sites. Epigenome-wide association studies (EWAS) …
[HTML][HTML] Current understanding on why ovarian cancer is resistant to immune checkpoint inhibitors
A Pawłowska, A Rekowska, W Kuryło… - International journal of …, 2023 - mdpi.com
The standard treatment of ovarian cancer (OC) patients, including debulking surgery and
first-line chemotherapy, is unsatisfactory because of recurrent episodes in the majority …
first-line chemotherapy, is unsatisfactory because of recurrent episodes in the majority …
[HTML][HTML] MicroRNAs in molecular classification and pathogenesis of breast tumors
Simple Summary Breast cancer is an ideal model of a heterogeneous disease that is
triggered by genetic changes in the normal mammary epithelial cells and manifest as …
triggered by genetic changes in the normal mammary epithelial cells and manifest as …
Anticancer analysis of CD44 targeted cyclosporine loaded thiolated chitosan nanoformulations for sustained release in triple-negative breast cancer
MS Abduh - International Journal of Nanomedicine, 2023 - Taylor & Francis
Introduction Cyclosporine (CsA), a potent immunosuppressive chemotherapeutic
medication, treats numerous cancers, particularly malignant carcinoma, acute leukemia, and …
medication, treats numerous cancers, particularly malignant carcinoma, acute leukemia, and …
[HTML][HTML] Circulating exosomal MiR-107 restrains tumorigenesis in diffuse large B-cell lymphoma by targeting 14-3-3η
J Liu, Y Han, S Hu, Y Cai, J Yang, S Ren… - Frontiers in Cell and …, 2021 - frontiersin.org
Exosomes, nanometer-sized membranous vesicles in body fluids, have emerged as
promising non-invasive biomarkers for cancer diagnosis. However, the function of exosomes …
promising non-invasive biomarkers for cancer diagnosis. However, the function of exosomes …
[HTML][HTML] ER Negative Breast Cancer and miRNA: There Is More to Decipher Than What the Pathologist Can See!
Breast cancer (BC), the most prevalent cancer in women, is a heterogenous disease.
Despite advancements in BC diagnosis, prognosis, and therapeutics, survival rates have …
Despite advancements in BC diagnosis, prognosis, and therapeutics, survival rates have …
Zinc transporter LIV1: A promising cell surface target for triple negative breast cancer
R Saravanan, V Balasubramanian… - Journal of Cellular …, 2022 - Wiley Online Library
Breast cancer is one of the leading causes contributing to the global cancer burden. The
triple negative breast cancer (TNBC) molecular subtype accounts for the most aggressive …
triple negative breast cancer (TNBC) molecular subtype accounts for the most aggressive …
[HTML][HTML] Overexpression of miR-125a-5p inhibits hepatocyte proliferation through the STAT3 regulation in vivo and in vitro
C Zhang, Y Zhao, Q Wang, J Qin, B Ye, C Xu… - International journal of …, 2022 - mdpi.com
microRNAs (miRNAs) are critically involved in liver regeneration (LR). miR-125a-5p (miR-
125a) is a tumor-suppressing miRNA, but its role in LR has not been studied. Our previous …
125a) is a tumor-suppressing miRNA, but its role in LR has not been studied. Our previous …
[HTML][HTML] Emerging landscape of molecular interaction networks: Opportunities, challenges and prospects
Network biology finds application in interpreting molecular interaction networks and
providing insightful inferences using graph theoretical analysis of biological systems. The …
providing insightful inferences using graph theoretical analysis of biological systems. The …
Blood-based epigenome-wide analyses on the prevalence and incidence of nineteen common disease states
Background Blood DNA methylation can inform us about the biological mechanisms that
underlie common disease states. Previous epigenome-wide analyses of common diseases …
underlie common disease states. Previous epigenome-wide analyses of common diseases …