Niacin (also known as “vitamin B3” or “vitamin PP”) includes two vitamers (nicotinic acid and
nicotinamide) giving rise to the coenzymatic forms nicotinamide adenine dinucleotide (NAD) …

Alcohol consumption remains one of the predominant causes of liver disease and liver-
related death worldwide. Intriguingly, dysregulation of the gut barrier is a key factor …

Rationale: Pulmonary arterial hypertension (PAH) is characterized by progressive
pulmonary vascular remodeling, accompanied by varying degrees of perivascular …

Niacin, as an antidyslipidemic drug, elicits a strong flushing response by release of
prostaglandin (PG) D2. However, whether niacin is beneficial for inflammatory bowel …

As pharmaceutical substances are highly used in human and veterinary medicine and
subsequently released in the environment, they represent emerging contaminants in the …

Neovascular age-related macular degeneration (nAMD) is a common and multifactorial
disease in the elderly that may lead to irreversible vision loss; yet the pathogenesis of AMD …

Niacin is a well established drug used to lower cholesterol and prevent cardiovascular
disease events. However, niacin also causes cutaneous flushing side effects due to release …

Background Alcohol abuse frequently causes niacin deficiency in association with the
development of alcoholic liver disease. The objective of the present study was to determine …

The number of approved new molecular entity drugs has been decreasing as the
pharmaceutical company investment in research and development is increasing. As we face …

Objective Previous studies have shown niacin has neuroprotective effects on the central
nervous system. However, its specific effect on spinal cord ischemia/reperfusion injury has …