[HTML][HTML] Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Digital transformation in toxicology: improving communication and efficiency in risk assessment

AV Singh, G Bansod, M Mahajan, P Dietrich… - ACS …, 2023 - ACS Publications
Toxicology is undergoing a digital revolution, with mobile apps, sensors, artificial
intelligence (AI), and machine learning enabling better record-keeping, data analysis, and …

[HTML][HTML] Evaluation of biological activity of natural compounds: current trends and methods

C Barba-Ostria, SE Carrera-Pacheco… - Molecules, 2022 - mdpi.com
Natural compounds have diverse structures and are present in different forms of life.
Metabolites such as tannins, anthocyanins, and alkaloids, among others, serve as a defense …

[HTML][HTML] Effects of Foliar Treatment with a Trichoderma Plant Biostimulant Consortium on Passiflora caerulea L. Yield and Quality

TE Şesan, AO Oancea, LM Ştefan, VS Mănoiu… - Microorganisms, 2020 - mdpi.com
The influence of spore concentration on the ability of a Trichoderma consortium to colonize
the Passiflora caerulea phyllosphere was evaluated by determining the effects of foliar …

[HTML][HTML] In vitro liver toxicity testing of chemicals: A pragmatic approach

A Tabernilla, B dos Santos Rodrigues… - International journal of …, 2021 - mdpi.com
The liver is among the most frequently targeted organs by noxious chemicals of diverse
nature. Liver toxicity testing using laboratory animals not only raises serious ethical …

[HTML][HTML] Salicylic acid Release from syndiotactic polystyrene Staple fibers

V Covelli, A Cozzolino, P Rizzo, M Rodriquez… - Molecules, 2023 - mdpi.com
Films and fibers of syndiotactic polystyrene (sPS), being amorphous or exhibiting
nanoporous crystalline (NC) or dense crystalline phases, were loaded with salicylic acid …

[HTML][HTML] In Vivo and In Silico Analgesic Activity of Ficus populifolia Extract Containing 2-O-β-D-(3′,4′,6′-Tri-acetyl)-glucopyranosyl-3-methyl Pentanoic Acid

HA Mohammed, AS Abouzied… - International Journal of …, 2023 - mdpi.com
Natural product-based structural templates have immensely shaped small molecule drug
discovery, and new biogenic natural products have randomly provided the leads and …

Rational approach toward COVID-19's main protease inhibitors: A hierarchical biochemoinformatics analysis

RS Bastos, CPO de Aguiar, JN Cruz… - International Journal of …, 2024 - mdpi.com
This study investigated the potential of selected compounds as inhibitors of SARS-CoV-2
Mpro through pharmacokinetic and toxicological analyses, molecular docking, and …

[HTML][HTML] Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia–Reperfusion Injury in Male Wistar Rats: Modulation of …

S Jeddi, S Gheibi, K Kashfi, M Carlström… - International journal of …, 2020 - mdpi.com
Decreased circulating levels of hydrogen sulfide (H2S) are associated with higher mortality
following myocardial ischemia. This study aimed at determining the long-term dose …

[HTML][HTML] Non-Invasive, Targeted Nanoparticle-Mediated Drug Delivery across a Novel Human BBB Model

S Kaya, B Callan, S Hawthorne - Pharmaceutics, 2023 - mdpi.com
The blood–brain barrier (BBB) is a highly sophisticated system with the ability to regulate
compounds transporting through the barrier and reaching the central nervous system (CNS) …